140198
Formamidoxime
99%
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About This Item
Formula condensata:
HC(=NOH)NH2
Numero CAS:
Peso molecolare:
60.06
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22
Prodotti consigliati
Saggio
99%
Punto di fusione
112-115 °C (lit.)
Temperatura di conservazione
2-8°C
Stringa SMILE
N\C=N\O
InChI
1S/CH4N2O/c2-1-3-4/h1,4H,(H2,2,3)
IONSZLINWCGRRI-UHFFFAOYSA-N
Applicazioni
Formamidoxime may be used as inhibitor of DNA synthesis.
Avvertenze
Warning
Indicazioni di pericolo
Classi di pericolo
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Dispositivi di protezione individuale
dust mask type N95 (US), Eyeshields, Gloves
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K P Flora et al.
Cancer research, 38(5), 1291-1295 (1978-05-01)
A series of amidoximes was prepared and evaluated for possible antitumor activity against L1210 leukemia. Three of the most active compounds in the L1210 system, formamidoxime, acetamidoxime, and 2-aminoacetamidoxime hydrochloride, were also active against P388 leukemia. Acetamidoxime was marginally active
F R Althaus et al.
The Journal of biological chemistry, 256(24), 13079-13084 (1981-12-25)
Microsomal proteins from cultured chick embryo hepatocytes were separated by polyacrylamide gel electrophoresis and their rate constants of degradation (Kd) were estimated using double isotope techniques. The proteins were found to be heterogeneous in their turnover rates, proteins, or subunits
Weiwen Zhao et al.
Organic & biomolecular chemistry, 9(22), 7647-7651 (2011-09-29)
The formamidoxime configurational Z isomer coupled with the pyridylbiscarboxamide conformational codon were used to fold planar, curved structures. When embedded into macrocycles, this folded motif promotes dimerization through π-π stacking and hydrogen-bonding and the formation of tubules akin to molecular
Yi Yan et al.
Chemical communications (Cambridge, England), 48(63), 7829-7831 (2012-07-04)
The partial positive charge of amide protons is used to promote macrocyclization and form crown-ether analogs. Their deprotonation generates very selective pH-switchable alkaline earth ion receptors only in the presence of an appropriate substrate.
Y Jia et al.
The American journal of physiology, 275(5 Pt 1), L895-L901 (1998-11-14)
Nitric oxide (NO) is known to be synthesized from L-arginine in a reaction catalyzed by NO synthase. Liver cytochrome P-450 enzymes also catalyze the oxidative cleavage of C==N bonds of compounds containing a -C(NH2)==NOH function, producing NO in vitro. The
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