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12804

Sigma-Aldrich

HBTU

≥98.0% (T), for peptide synthesis

Sinonimo/i:

N,N,N′,N′-Tetramethyl-O-(1H-benzotriazol-1-yl)uronium hexafluorophosphate, O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate

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About This Item

Formula empirica (notazione di Hill):
C11H16F6N5OP
Numero CAS:
94790-37-1
Peso molecolare:
379.24
Beilstein:
7328329
Numero CE:
423-020-5
Numero MDL:
MFCD00075445
Codice UNSPSC:
12352107
ID PubChem:
57647025
NACRES:
NA.22

product name

HBTU, ≥98.0% (T)

Livello qualitativo

200

Saggio

≥98.0% (T)

Forma fisica

solid

Impiego in reazioni chimiche

reaction type: Coupling Reactions

Punto di fusione

200 °C (dec.) (lit.)

Solubilità

acetonitrile: 0.1 g/mL, clear

applicazioni

peptide synthesis

Temperatura di conservazione

2-8°C

Stringa SMILE

F[P-](F)(F)(F)(F)F.CN(C)C(\On1nnc2ccccc12)=[N+](/C)C

InChI

1S/C11H16N5O.F6P/c1-14(2)11(15(3)4)17-16-10-8-6-5-7-9(10)12-13-16;1-7(2,3,4,5)6/h5-8H,1-4H3;/q+1;-1
UQYZFNUUOSSNKT-UHFFFAOYSA-N

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Descrizione generale

HBTU is a peptide coupling agent used in Fmoc-based solid-phase peptide synthesis.

Applicazioni

HBTU is a peptide coupling agent for peptide synthesis. It has also been used in standard Fmoc-based solid-phase peptide synthesis (SPPS) protocol.
Recent studies show that crystal as well as solution structure of this coupling agent is a guanidinium N-oxide and not an uronium compound; Coupling reagent for peptide synthesis; advantages are: very low racemization, simple reaction conditions, very short reaction time, and high yields.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H317

Classi di pericolo

Skin Sens. 1A

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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