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119660

Sigma-Aldrich

Tris(2-chloroethyl) phosphate

97%

Sinonimo/i:

Phosphoric acid tris(2-chloroethyl) ester

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25 G
CHF 46.20

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25 G
CHF 46.20

About This Item

Formula condensata:
(ClCH2CH2O)3P(O)
Numero CAS:
115-96-8
Peso molecolare:
285.49
Numero CE:
204-118-5
Numero MDL:
MFCD00000967
Codice UNSPSC:
12352100
ID PubChem:
24847295
NACRES:
NA.22

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Tensione di vapore

<10 mmHg ( 25 °C)

Livello qualitativo

100

Saggio

97%

Indice di rifrazione

n20/D 1.472 (lit.)

P. ebollizione

192 °C/10 mmHg (lit.)

Solubilità

H2O: soluble 7.82 g/L

Densità

1.39 g/mL at 25 °C (lit.)

Stringa SMILE

ClCCOP(=O)(OCCCl)OCCCl

InChI

1S/C6H12Cl3O4P/c7-1-4-11-14(10,12-5-2-8)13-6-3-9/h1-6H2
HQUQLFOMPYWACS-UHFFFAOYSA-N

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Descrizione generale

Tris(2-chloroethyl) phosphate is used as a flame retardant [1]in plastics, especially inflexible foams used in automobiles and furniture and in rigid foams used for building insulation[2].

Applicazioni

Tris(2-chloroethyl) phosphate was used in dynamic air sampling of airborne organophosphate triesters using a solid-phase microextraction device[3].

Pittogrammi

Health hazardExclamation mark
GHS08,GHS07

Avvertenze

Danger

Indicazioni di pericolo

H302,H351,H360

Classi di pericolo

Acute Tox. 4 Oral - Carc. 2 - Repr. 1B

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

449.6 °F - closed cup

Punto d’infiammabilità (°C)

232 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificati d'analisi (COA)

Lot/Batch Number
MKCM5665
MKCB1019V
U08057V
S25669V
S25669

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H A Tilson et al.
Toxicology and applied pharmacology, 106(2), 254-269 (1990-11-01)
Adult female, Fischer-344 rats were exposed to 275 mg/kg of tris(2-chloroethyl)phosphate (TRCP) by gavage. TRCP produced consistent signs of convulsive activity within 60-90 min after dosing and extensive loss of CAT hippocampal pyramidal cells when examined 7 days after dosing.
H B Matthews et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 20(4), 477-485 (1993-05-01)
Previous short-term studies of tris(2-chloroethyl)phosphate (TRCP), a flame retardant used in industrial and consumer products, demonstrated that repeated administration of 350 mg TRCP/kg body wt by oral gavage resulted in necrosis of pyramidal neurons in the CA1 region of the
H B Matthews et al.
Toxicology and industrial health, 6(1), 1-15 (1990-01-01)
Tris(2-chloroethyl)phosphate (TRCP), a flame-retardant plasticizer used in plastics, polymeric foams and synthetic fibers, was studied as part of the National Toxicology Program's class study of phosphate flame-retardants. TRCP was administered at 0, 22, 44, 88, 175 and 350 mg/kg to
Thorvald Staaf et al.
Journal of environmental monitoring : JEM, 7(9), 883-887 (2005-08-27)
In this study the occurrence of ten organophosphate triesters in indoor air at 29 different locations was investigated. They were detected at all locations and a total of ten compounds were identified. The predominant compounds were the chlorinated compounds tris(chloroisopropyl)
L T Burka et al.
Drug metabolism and disposition: the biological fate of chemicals, 19(2), 443-447 (1991-03-01)
Tris(2-chloroethyl) phosphate (TRCP), a flame retardant, produces a dose-, sex-, and species-dependent lesion in the hippocampal region of the brain following subchronic oral administration. This lesion is more common and more severe in female F344 rats than in male F344
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