PTPRC
protein tyrosine phosphatase, receptor type, C
Sinonimi:
B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
Specie:
Human PTPRC (5788), Mouse Ptprc (19264), Rat Ptprc (24699), Zebrafish ptprc (559154), chicken PTPRC (386580), domestic cat PTPRC (101097123), Horse PTPRC (100061950), dog PTPRC (490255), sheep PTPRC (101102917), cow PTPRC (407152) ...Più
ID UniProtKB:
ID gene:
- Human(5788) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
- Mouse(19264) protein tyrosine phosphatase, receptor type, C
- Rat(24699) protein tyrosine phosphatase, receptor type, C
- Zebrafish(559154) protein tyrosine phosphatase, receptor type, C
- chicken(386580) protein tyrosine phosphatase, receptor type, C
- domestic cat(101097123) protein tyrosine phosphatase, receptor type, C
- Horse(100061950) protein tyrosine phosphatase, receptor type, C
- dog(490255) protein tyrosine phosphatase, receptor type, C
- sheep(101102917) protein tyrosine phosphatase, receptor type, C
- cow(407152) protein tyrosine phosphatase, receptor type, C
- Domestic Rabbit(100358807) protein tyrosine phosphatase, receptor type, C
- naked mole-rat(101710515) protein tyrosine phosphatase, receptor type, C
- domestic guinea pig(100730564) protein tyrosine phosphatase, receptor type, C
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Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-CD45 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Anti-CD45 Antibody, clone IBL-5/25, clone IBL-5/25, from rat,
Reattività con
mouse
Applicazione
flow cytometry
immunohistochemistry
immunohistochemistry
Anti-CD45 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
western blot
Anti-CD45 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-CD45 Antibody, clone F10-89-4, clone F10-89-4, from mouse, purified by affinity chromatography,
Reattività con
human, mouse, rat
Applicazione
flow cytometry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Proteins
Numero di prodotto
Descrizione
Specie
CD45 Protein, 10 µg, His6-tagged, recombinant, human CD45, amino acids 598-end, for use in Enzyme Assays.,
Specie
human
CD45 Active human, recombinant, expressed in baculovirus infected insect cells, ≥90% (SDS-PAGE),
Specie
human
PTPRC (592-end), active, GST tagged from mouse, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
mouse