Passa al contenuto
Merck

NDUFA5

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5

Sinonimi:
B13, CI-13KD-B, CI-13kB, NUFM, UQOR13
Specie:
ID UniProtKB:
ID gene:
  • Human(4698) Summary: The human NDUFA5 gene codes for the B13 subunit of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. The high degree of conservation of NDUFA5 extending to plants and fungi indicates its functional significance in the enzyme complex. The protein localizes to the inner mitochondrial membrane as part of the 7 component-containing, water soluble 'iron-sulfur protein' (IP) fraction of complex I, although its specific role is unknown. It is assumed to undergo post-translational removal of the initiator methionine and N-acetylation of the next amino acid. The predicted secondary structure is primarily alpha helix, but the carboxy-terminal half of the protein has high potential to adopt a coiled-coil form. The amino-terminal part contains a putative beta sheet rich in hydrophobic amino acids that may serve as mitochondrial import signal. Related pseudogenes have also been identified on four other chromosomes. [provided by RefSeq, Jul 2008]
  • Mouse(68202) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
  • Rat(25488) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 5
  • naked mole-rat(101701548) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa
  • domestic guinea pig(100723200) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
  • domestic cat(101092508) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa
  • cow(327714) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa
  • sheep(101123463) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa
  • Zebrafish(541328) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
  • chicken(417753) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa
  • dog(475214) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-NDUFA5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
Anti-NDUFA5 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot
Anti-NDUFA5 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-NDUFA5 antibody produced in mouse, clone 4A2, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Metformin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Metformin hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human
1,1-Dimethylbiguanide hydrochloride, 97%,
Specie
human
Metformin hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Metformin hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human NDUFA5 (1),
Specie
human
MISSION® esiRNA, targeting human NDUFA5 (2),
Specie
human
MISSION® esiRNA, targeting mouse Ndufa5,
Specie
mouse