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Merck

IMPDH2

IMP (inosine 5'-monophosphate) dehydrogenase 2

Sinonimi:
IMPD2, IMPDH-II
Specie:
Human IMPDH2 (3615), Mouse Impdh2 (23918), Rat Impdh2 (301005), dog IMPDH2 (476630), Zebrafish impdh2 (317745), domestic guinea pig Impdh2 (100730768), naked mole-rat Impdh2 (101701391), domestic cat IMPDH2 (101080693), cow IMPDH2 (511969), sheep IMPDH2 (101107823) ...Più
ID UniProtKB:
P12268, Q6LEF3
ID gene:
  • Human(3615) Summary: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
  • Mouse(23918) inosine 5'-phosphate dehydrogenase 2
  • Rat(301005) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • dog(476630) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Zebrafish(317745) IMP (inosine monophosphate) dehydrogenase 2
  • domestic guinea pig(100730768) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • naked mole-rat(101701391) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • domestic cat(101080693) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • cow(511969) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • sheep(101107823) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Domestic Rabbit(100355621) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • chicken(416058) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Horse(100063255) IMP (inosine 5'-monophosphate) dehydrogenase 2

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
HPA001400
Anti-IMPDH2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
western blot
ST1578
Anti-IMPDH2 Mouse mAb (1E12-B6), liquid, clone 1E12-B6, Calbiochem®,
Reattività con
human
Applicazione
WH0003615M1
Monoclonal Anti-IMPDH2 antibody produced in mouse, clone 1E12-B6, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunoprecipitation (IP)
western blot
SAB1410715
Anti-IMPDH2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
immunofluorescence
western blot
SAB1406037
Anti-IMPDH2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
N4505
β-Nicotinamide adenine dinucleotide, reduced dipotassium salt, ,
Specie
human
R9644
Ribavirin, antiviral,
Specie
human
A4882
6-Thioguanine, ≥98%,
Specie
human
M5255
Mycophenolic acid, ≥98%,
Specie
human
M3536
Mycophenolic acid, powder, BioReagent, suitable for cell culture,
Specie
human

Proteins

N° Catalogo
Descrizione
Specie
I1782
Inosine Monophosphate Dehydrogenase Type II human, recombinant, expressed in E. coli,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
EHU027541
MISSION® esiRNA, targeting human IMPDH2,
Specie
human
EMU094871
MISSION® esiRNA, targeting mouse Impdh2,
Specie
mouse