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Merck

HTR5A

5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled

Sinonimi:
5-HT5A
Specie:
ID UniProtKB:
ID gene:
  • Human(3361) Summary: The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008]
  • Mouse(15563) 5-hydroxytryptamine (serotonin) receptor 5A
  • Rat(25689) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • cow(541200) 5-hydroxytryptamine (serotonin) receptor 5A
  • Horse(100063709) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • domestic cat(101084611) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • Zebrafish(100038775) 5-hydroxytryptamine (serotonin) receptor 5A
  • dog(482814) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • sheep(101116905) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • naked mole-rat(101723065) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • domestic guinea pig(100379278) 5-hydroxytryptamine (serotonin) receptor 5A
  • chicken(428409) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
5-Carboxamidotryptamine maleate salt, powder, ≥98% (HPLC),
Specie
human, rat
Quipazine maleate salt, ,
Specie
human

Small Molecule - Allosteric Modulator

N° Catalogo
Descrizione
Specie
DCEBIO, ≥98% (HPLC), solid,
Specie
human

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
5-Carboxamidotryptamine maleate salt, powder, ≥98% (HPLC),
Specie
human, rat
Amisulpride, ≥98% (HPLC),
Specie
human
Amisulpride for system suitability, British Pharmacopoeia (BP) Reference Standard,
Specie
human
Amisulpride, European Pharmacopoeia (EP) Reference Standard,
Specie
human
Amisulpride for system suitability, European Pharmacopoeia (EP) Reference Standard,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-HTR5A antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
ELISA
immunofluorescence

western blot
Anti-HTR5A antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunohistochemistry
Anti-HTR5A (AB1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunohistochemistry
Anti-HTR5A (AB2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
bovine, dog, guinea pig, horse, human, monkey, mouse, rat
Applicazione
ELISA
immunohistochemistry

Small Molecule - Blocker

N° Catalogo
Descrizione
Specie
Trimipramine maleate salt, ≥98% (TLC), powder,
Specie
human
Zimelidine dihydrochloride, solid,
Specie
human

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Specie
human
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Specie
human
Fluoxetine hydrochloride, solid,
Specie
human
Reserpine, ,
Specie
human
Sertraline hydrochloride, ≥98% (HPLC),
Specie
human

Small Molecule - Ligand

N° Catalogo
Descrizione
Specie
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Specie
human

Small Molecule - Metabolite

N° Catalogo
Descrizione
Specie
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Specie
human

Small Molecule - Precursor

N° Catalogo
Descrizione
Specie
5-Hydroxy-L-tryptophan, powder,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human HTR5A,
Specie
human