DNASE1
deoxyribonuclease I
Sinonimi:
DNL1, DRNI
Specie:
Human DNASE1 (1773), Mouse Dnase1 (13419), Rat Dnase1 (25633), naked mole-rat Dnase1 (101713435), domestic guinea pig Dnase1 (100718441), sheep DNASE1 (101122154), Horse DNASE1 (100034219), cow DNASE1 (282217), Domestic Rabbit DNASE1 (100009513), dog DNASE1 (403413) ...Più
ID UniProtKB:
ID gene:
- Human(1773) Summary: This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
- Mouse(13419) deoxyribonuclease I
- Rat(25633) deoxyribonuclease I
- naked mole-rat(101713435) deoxyribonuclease I
- domestic guinea pig(100718441) deoxyribonuclease I
- sheep(101122154) deoxyribonuclease I
- Horse(100034219) deoxyribonuclease I
- cow(282217) deoxyribonuclease I
- Domestic Rabbit(100009513) deoxyribonuclease I
- dog(403413) deoxyribonuclease I
- domestic cat(101096195) deoxyribonuclease I
- chicken(395725) deoxyribonuclease I
- Zebrafish(436947) deoxyribonuclease I
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-DNASE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
western blot
Anti-DNASE1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, human, rat
Applicazione
western blot
Anti-DNASE1 (N-terminal) antibody produced in rabbit FITC conjugated, affinity isolated antibody,
Reattività con
bovine, human, rat
Applicazione
Anti-DNASE1 (N-terminal) antibody produced in rabbit HRP conjugated, affinity isolated antibody,
Reattività con
bovine, human, rat
Applicazione
Proteins
N° Catalogo
Descrizione
Specie
Desossiribonucleasi I, Type II-S, lyophilized powder, Protein ≥80 %, ≥2,000 units/mg protein,
Specie
Desossiribonucleasi I, Type II, lyophilized powder, Protein ≥80 %, ≥2,000 units/mg protein,
Specie
DNase I recombinant, grade I, from bovine pancreas, expressed in Pichia pastoris,
Specie
cow