Passa al contenuto
Merck

CDH1

cadherin 1, type 1, E-cadherin (epithelial)

Sinonimi:
Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Specie:
ID UniProtKB:
ID gene:
  • Human(999) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
  • Mouse(12550) cadherin 1
  • Rat(83502) cadherin 1
  • dog(442858) cadherin 1, type 1, E-cadherin (epithelial)
  • chicken(415860) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(100294601) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic guinea pig(100726210) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic cat(101095391) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(101119747) cadherin 1, type 1, E-cadherin (epithelial)
  • naked mole-rat(101719565) cadherin 1, type 1, E-cadherin (epithelial)
  • Zebrafish(114424) cadherin 1, epithelial
  • cow(282637) cadherin 1, type 1, E-cadherin (epithelial)

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Mouse E-Cadherin ELISA Kit, for serum, plasma and cell culture supernatant,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-E-Cadherin Antibody, serum, Upstate®,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-E-cadherin antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-E-Cadherin antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-E-Cadherin Antibody, clone 67A4, Azide Free, clone 67A4, Chemicon®, from mouse,
Reattività con
human
Applicazione
flow cytometry
immunofluorescence
Anti-E-Cadherin/CD324 Antibody, clone 19A11, ,
Reattività con
canine, human
Applicazione
ELISA
immunocytochemistry

inhibition assay

western blot

Cell Lines

Numero di prodotto
Descrizione
Specie
MCF10A CELLS CDH1 (-/-), ,
Specie
human

Proteins

Numero di prodotto
Descrizione
Specie
E-Cadherin human, recombinant, expressed in E. coli, 0.5 mg protein/mL,
Specie
human
E-Cadherin/Fc Chimera from mouse, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Specie
mouse

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human CDH1,
Specie
human
MISSION® esiRNA, targeting mouse Cdh1,
Specie
mouse