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Merck

CDH1

cadherin 1, type 1, E-cadherin (epithelial)

Sinonimi:
Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Specie:
ID UniProtKB:
ID gene:
  • Human(999) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
  • Mouse(12550) cadherin 1
  • Rat(83502) cadherin 1
  • dog(442858) cadherin 1, type 1, E-cadherin (epithelial)
  • chicken(415860) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(100294601) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic guinea pig(100726210) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic cat(101095391) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(101119747) cadherin 1, type 1, E-cadherin (epithelial)
  • naked mole-rat(101719565) cadherin 1, type 1, E-cadherin (epithelial)
  • Zebrafish(114424) cadherin 1, epithelial
  • cow(282637) cadherin 1, type 1, E-cadherin (epithelial)

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ELISA

N° Catalogo
Descrizione
Specie
Mouse E-Cadherin ELISA Kit, for serum, plasma and cell culture supernatant,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-E-cadherin antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Pan-Cadherin antibody, Mouse monoclonal, clone CH-19, purified from hybridoma cell culture,
Reattività con
psammomys (sand rat), bovine, canine, cat, chicken, ferret, frog, guinea pig, hamster, human, monkey, mouse, rabbit, rat, snake
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-E-Cadherin Antibody, serum, Upstate®,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-E-Cadherin antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP64, affinity isolated antibody,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Monoclonal Anti-Uvomorulin/E-Cadherin antibody produced in rat, clone DECMA-1, purified from hybridoma cell culture,
Reattività con
dog, mouse
Applicazione
immunofluorescence
immunoprecipitation (IP)

western blot

Cell Lines

N° Catalogo
Descrizione
Specie
MCF10A CELLS CDH1 (-/-), ,
Specie
human

Proteins

N° Catalogo
Descrizione
Specie
E-Cadherin human, recombinant, expressed in E. coli, 0.5 mg protein/mL,
Specie
human
E-Cadherin/Fc Chimera from mouse, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Specie
mouse

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Cdh1,
Specie
mouse
MISSION® esiRNA, targeting human CDH1,
Specie
human