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Merck

CDC25B

cell division cycle 25B

Sinonimi:
Specie:
ID UniProtKB:
ID gene:
  • Human(994) Summary: CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008]
  • Mouse(12531) cell division cycle 25B
  • Rat(171103) cell division cycle 25B
  • domestic guinea pig(100716851) cell division cycle 25B
  • naked mole-rat(101701077) cell division cycle 25B
  • cow(505847) cell division cycle 25 homolog B (S. pombe)
  • dog(485790) cell division cycle 25 homolog B (S. pombe)
  • Horse(100052425) cell division cycle 25 homolog B (S. pombe)
  • domestic cat(101092757) cell division cycle 25 homolog B (S. pombe)
  • sheep(101120511) cell division cycle 25 homolog B (S. pombe)

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-CDC25B antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-CDC25B (pSer353) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry

western blot
Anti-CDC25B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Monoclonal Anti-CDC25B antibody produced in mouse, clone 7E8, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
Anti-phospho-Cdc25b (pSer149) antibody produced in rabbit, affinity isolated antibody,
Reattività con
mouse
Applicazione
western blot

Cell Lines

N° Catalogo
Descrizione
Specie
MCF10A CELLS CDC25B (-/-), ,
Specie
human

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
NSC 95397, ≥97% (HPLC),
Specie
human
NSC 663284, ≥98% (HPLC), solid,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human CDC25B,
Specie
human
MISSION® esiRNA, targeting mouse Cdc25b,
Specie
mouse