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Merck

AGT

angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

Sinonimi:
ANHU, SERPINA8
Specie:
Human AGT (183), Mouse Agt (11606), Rat Agt (24179), Thale Cress AGT (815822), Zebrafish agt (322485), fruit fly agt (40816), chicken AGT (421543), dog AGT (403783), domestic cat AGT (101093714), cow AGT (527114) ...Più
ID UniProtKB:
P01019, Q16358, Q16359, Q96F91
ID gene:
  • Human(183) Summary: The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008]
  • Mouse(11606) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • Rat(24179) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • Thale Cress(815822) alanine--glyoxylate aminotransferase
  • Zebrafish(322485) angiotensinogen
  • fruit fly(40816) O-6-alkylguanine-DNA alkyltransferase
  • chicken(421543) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • dog(403783) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • domestic cat(101093714) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • cow(527114) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • sheep(101119440) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • sheep(100294599) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • naked mole-rat(101717217) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • domestic guinea pig(100724950) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

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ELISA

N° Catalogo
Descrizione
Specie
RAB0010
Angiotensin II EIA Kit, for serum, plasma, culture supernatant and cell lysates,
Specie
human
RAB1021
Human Angiotensinogen ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
MAB4051
Anti-Angiotensin Converting Enzyme Antibody, clone 9B9, clone 9B9, Chemicon®, from mouse,
Reattività con
feline, hamster, human, monkey, rat
Applicazione
ELISA
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
HPA001557
Anti-AGT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
ZRB1021
Anti-Angiotensinogen Antibody, clone 1B12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human
Applicazione
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
SAB1403532
Monoclonal Anti-AGT antibody produced in mouse, clone 3C10, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunohistochemistry
western blot
SAB1405438
Anti-AGT antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot

Proteins

N° Catalogo
Descrizione
Specie
A9525
Angiotensina II umana, ≥93% (HPLC), powder,
Specie
human
A9650
Angiotensin I human acetate salt hydrate, ≥90% (HPLC), powder, suitable for mammalian cell culture,
Specie
human
A9202
Angiotensin Fragment 1-7 acetate salt hydrate, ≥90% (HPLC), powder,
Specie
human
A2562
Angiotensinogen from human plasma, ≥80% (SDS-PAGE), lyophilized powder,
Specie
human
176870
Angiotensinogen, Human Plasma, Native angiotensinogen from human plasma that is cleaved by renin to generate angiotensin I. It is a part of the renin-angiotensin system that regulates blood pressure and fluid balance.,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
EHU131721
MISSION® esiRNA, targeting human AGT,
Specie
human