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1653004

USP

Theophylline

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

1,3-Dimethylxanthine, 2,6-Dihydroxy-1,3-dimethylpurine, 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione

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About This Item

Formule empirique (notation de Hill) :
C7H8N4O2
Numéro CAS:
58-55-9
Poids moléculaire :
180.16
Beilstein:
13463
Numéro MDL:
MFCD00079619
Code UNSPSC :
41116107
ID de substance PubChem :
329751262
Nomenclature NACRES :
NA.24

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Qualité

pharmaceutical primary standard

Famille d'API

theophylline

Fabricant/nom de marque

USP

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

CN1C(=O)N(C)c2[nH]cnc2C1=O

InChI

1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9)

Clé InChI

ZFXYFBGIUFBOJW-UHFFFAOYSA-N

Informations sur le gène

human ... ADORA1(134) , ADORA2A(135) , ADORA2B(136) , ADORA3(140) , PDE3A(5139) , PDE3B(5140) , PDE4A(5141) , PDE4B(5142) , PDE4C(5143) , PDE4D(5144)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Theophylline USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Aminophylline
  • Aminophylline Delayed-Release Tablets
  • Aminophylline Injection
  • Aminophylline Oral Solution
  • Aminophylline Rectal Solution
  • Aminophylline Tablets
  • Dimenhydrinate

Actions biochimiques/physiologiques

Phosphodiesterase inhibitor; diuretic; cardiac stimulant; muscle relaxant; asthma medication.

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

PHR1151

Theophylline melting point standard, Pharmaceutical Secondary Standard; Certified Reference Material

T0800000

Theophylline, European Pharmacopoeia (EP) Reference Standard

1653117

Theophylline melting point standard, United States Pharmacopeia (USP) Reference Standard

1077708

8-Bromotheophylline, United States Pharmacopeia (USP) Reference Standard

1653048

Theophylline Related Compound D, United States Pharmacopeia (USP) Reference Standard

1653037

Theophylline Related Compound C, United States Pharmacopeia (USP) Reference Standard

1653026

Theophylline Related Compound B, United States Pharmacopeia (USP) Reference Standard

1653060

Theophylline Related Compound F, United States Pharmacopeia (USP) Reference Standard

BP327

Theophylline, British Pharmacopoeia (BP) Reference Standard

PHR2588

Theophylline Related Compound F, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2541

Theophylline Related Compound F, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2551

Theophylline Related Compound D, Pharmaceutical Secondary Standard; Certified Reference Material

1121038

8-Chlorotheophylline, United States Pharmacopeia (USP) Reference Standard

Pictogrammes

Skull and crossbonesHealth hazard
GHS06,GHS08

Mention d'avertissement

Danger

Mentions de danger

H301,H360D

Classification des risques

Acute Tox. 3 Oral - Repr. 1B

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

F S F Ram et al.
Respiratory medicine, 99(2), 135-144 (2005-02-18)
To determine the efficacy of oral theophylline compared with placebo in people with stable chronic obstructive pulmonary disease (COPD). Systematic review of randomized-controlled trials comparing oral theophylline with placebo for a minimum of 7 days in people with stable COPD.
Mazen Al-Alawi et al.
The American journal of medicine, 127(5), 370-378 (2014-01-02)
Global estimates on aging predict an increased burden of asthma in the older population. Consequently, its recognition, diagnosis, and management in clinical practice require optimization. This review aims to provide an update for clinicians, highlighting advances in the understanding of
Bing Dai et al.
American journal of kidney diseases : the official journal of the National Kidney Foundation, 60(3), 360-370 (2012-04-21)
Whether treatment with adenosine receptor antagonists such as theophylline can prevent contrast-induced acute kidney injury (AKI) remains controversial. We conducted a meta-analysis of randomized controlled trials using MEDLINE (1966 to July 2011), EMBASE (1980 to July 2011), Web of Science
Diego Caccavo et al.
Molecular pharmaceutics, 12(2), 474-483 (2014-12-17)
In this work the behavior of hydrogel-based matrices, the most widespread systems for oral controlled release of pharmaceuticals, has been mathematically described. In addition, the calculations of the model have been validated against a rich set of experimental data obtained
Amy T Ma et al.
Applied and environmental microbiology, 80(21), 6704-6713 (2014-08-26)
Cyanobacteria are photosynthetic bacteria that are currently being developed as biological production platforms. They derive energy from light and carbon from atmospheric carbon dioxide, and some species can fix atmospheric nitrogen. One advantage of developing cyanobacteria for renewable production of
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