SRP4388

SDF-1alpha (CXCL12) from mouse

recombinant, expressed in E. coli, ≥99% (SDS-PAGE), ≥99% (HPLC)

• Synonyme(s) : CXCL12, PBSF, Pre-B cell growth-stimulating factor, SDF-1, chemokine (C-X-C motif) ligand 12, hIRH
• Numéro MDL: MFCD01867605
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: mouse
• Produit recombinant: expressed in E. coli
• Pureté: ≥99% (HPLC); ≥99% (SDS-PAGE)
• Forme: lyophilized
• Puissance: 50-100 ng/mL
• Poids mol.: ~7.9 kDa
• Conditionnement: pkg of 10 μg
• Conditions de stockage: avoid repeated freeze/thaw cycles
• Impuretés: endotoxin, tested
• Numéro d'accès NCBI: P40224
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Informations sur le gène: mouse ... Sdf1(20315)

Description

Description générale

Stromal Cell-Derived Factor-1α (SDF-1α) is a recently discovered protein belonging to the α-chemokine (C-X-C) family of cytokines. Recombinant mouse SDF-1α is a 7.9kDa protein containing 68 amino acids residues.

Actions biochimiques/physiologiques

Stromal Cell-Derived Factor-1α (SDF-1α) is a pleiotropic chemokine. It works as a chemoattractant for T- and B-lymphocytes and inflammatory monocytes. In neural stem cells, SDF-1α is needed for proliferation, survival, migration, intercellular interaction and guidance to neuronal axon. It is responsible for pathogenic inflammation in the central nervous system (CNS). It also controls BMP (bone morphogenic protein)-associated osteogenic differentiation.

Forme physique

Lyophilized from 10 mM acetic acid. The protein may appear as a haze or film, which is difficult to see at the bottom of the vial.

Reconstitution

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitution in water to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers.

Informations sur la sécurité

• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable