SML2470

GYY4137 sodium, dichloromethane-free

≥98% (HPLC)

• Synonyme(s) : (4-Methoxyphenyl)-4-morpholinyl-phosphinodithioic acid, sodium salt, GYY4137 Na salt, GYY4137 sodium salt, Na-GYY4137, Sodium 4-methoxyphenyl(morpholino)phosphinodithioate, Sodium GYY4137
• Formule empirique (notation de Hill): C₁₁H₁₅NNaO₂PS₂
• Numéro CAS: 1975149-21-3
• Poids moléculaire : 311.34
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: powder
• Conditions de stockage: desiccated
• Couleur: white to beige
• Solubilité: H₂O: 2 mg/mL, clear
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Chaîne SMILES: [S-]P(C1=CC=C(C=C1)OC)(N2CCOCC2)=S.[Na+]
• InChI: 1S/C11H16NO2PS2.Na/c1-13-10-2-4-11(5-3-10)15(16,17)12-6-8-14-9-7-12;/h2-5H,6-9H2,1H3,(H,16,17);/q;+1/p-1
• Clé InChI: ZFQXKWOUNSKHAG-UHFFFAOYSA-M

Description

Actions biochimiques/physiologiques

GYY4137 sodium (Na-GYY4137) is a dichloromethane-free, water-soluble sodium salt form of the slow-releasing hydrogen sulfide (H2S) donor GYY4137. Na-GYY4137 is devoid of potential off-target effects associated with the use of dichloromethane-complexed GYY4137 morpholine salt form. Morpholine is biologically active and toxic (LD₅₀ range of 300-500 mg/kg in rodents), while dichloromethane is carcinogenic and can metabolize in vivo to carbon monoxide, causing unintended CO-dependent effects.

Water soluble, non-toxic alternative to the dichloromethane-containing morpholine salt form of the hydrogen sulfide (H2S) donor GYY4137.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable