Cluster of differentiation 81 (CD81) is expressed on the oocyte surface. It consists of five large helical segments and belongs to the tetraspanin family. The gene encoding this protein is localized on human chromosome 11p15.5.
The antibody M38 reacts with CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.
Immunogène
MOLT-4 (human T-ALL cell line)
Application
The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 1 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
Actions biochimiques/physiologiques
Cluster of differentiation 81 (CD81) has a role in membrane organization, cell-cell interactions, cellular fusion and protein trafficking. It is also involved in receptor clustering and signaling. CD81 is overexpressed in cancers.
Caractéristiques et avantages
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Forme physique
Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
10 - Combustible liquids
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Faites votre choix parmi les versions les plus récentes :
A role for CD81 and hepatitis C virus in hepatoma mobility.
Viruses, 6, 1454-1472 (2014)
CD81 as a tumor target.
Vences-Catalan F
Biochemical Society Transactions, 45, 531-535 (2017)
Oligomerization of the Tetraspanin CD81 via the Flexibility of Its ?-Loop.
Schmidt TH
Biophysical Journal, 110, 2463-2474 (2016)
A microarray-based DNA methylation study of
glioblastoma multiforme
Martinez R
Epigenetics, 4, 255-264 (2009)
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