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SAB4301137

Sigma-Aldrich

Anti-ACTIN antibody produced in rabbit

affinity isolated antibody

Synonyme(s) :

ACTB

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Poids mol.

42 kDa

Espèces réactives

plant

Concentration

1 mg/mL

Technique(s)

western blot: 1:500-1:2000 (Cell Lysate)

Isotype

IgG

Numéro d'accès

NP_190236.1

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

Arabidopsis thaliana ... ACT12(823805)

Description générale

Actin/ actin β(ACTB) is encoded by the gene mapped to human chromosome 7p15-p12. In mammals, actin protein consists of six different isoforms encoded by separate genes. The four isoforms αskeletal-actin, αcardiac-actin, αsmooth-actin, and γ smooth-actin are expressed in skeletal, cardiac and smooth muscle. The other two isoforms, β cyto-actin and γ cyto-actin are ubiquitously expressed.

Spécificité

The antibody detects endogenous levels of total ACTIN protein.

Immunogène

Synthetic peptide corresponding to residues near the N terminal of Arabidopsis thaliana actin

Actions biochimiques/physiologiques

Actin plays a vital role in various cellular processes, such as cell division, migration, junction formation, chromatin remodeling, transcriptional regulation, vesicle trafficking, and cell shape regulation. Polymorphism in the smooth muscle α-actin (ACTA2) is associated with the development of thoracic aortic aneurysms and dissections.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Elizabeth Feldeverd et al.
Frontiers in plant science, 11, 610052-610052 (2021-01-16)
Plants adapt to heat via thermotolerance pathways in which the activation of protein folding chaperones is essential. In eukaryotes, protein disulfide isomerases (PDIs) facilitate the folding of nascent and misfolded proteins in the secretory pathway by catalyzing the formation and
Mutations in smooth muscle ?-actin (ACTA2) lead to thoracic aortic aneurysms and dissections.
Guo D C, et al.
Nature Genetics, 39(12), 1488-1488 (2007)
Sublocalization of an invasion-inducing locus and other genes on human chromosome 7.
Habets G G M, et al.
Cytogenetic and genome research, 60(3-4), 200-205 (1992)
Dong Meng et al.
The Plant journal : for cell and molecular biology, 106(5), 1278-1297 (2021-03-19)
Calcineurin B-like (CBL)-interacting protein kinases (CIPKs) play a central role in Ca2+ signalling and promote drought tolerance in plants. The CIPK gene family in pigeon pea (Cajanus cajan L.), a major food crop affected by drought, has not previously been
Lucie Horakova et al.
Frontiers in physiology, 13, 1033130-1033130 (2023-01-27)
Ectodysplasin (Eda) plays important roles in both shaping the developing tooth and establishing the number of teeth within the tooth row. Sonic hedgehog (Shh) has been shown to act downstream of Eda and is involved in the initiation of tooth

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