SAB4200639

Monoclonal Anti-DHX9/RHA antibody produced in rat

clone 8E3, purified from hybridoma cell culture

• Synonyme(s) : Anti-ATP−dependent RNA helicase A, Anti-ATP-dependent RNA helicase A, Anti-DDX9, Anti-DEAD/H (Asp−Glu−Ala−Asp/His) box polypeptide 9, Anti-DEAH (Asp−Glu−Ala−His) box polypeptide 9, Anti-DEAH (Asp-Glu-Ala-His) box helicase 9, Anti-DEAH (Asp-Glu-Ala-His) box polypeptide 9, Anti-DEAH box protein 9, Anti-DHX9, Anti-Ddx9, Anti-HEL-5, Anti-LKP, Anti-NDH2, Anti-NDHII, Anti-Nuclear DNA helicase II (NDHII), Anti-leukophysin, Anti-mHEL-5, Anti-nuclear DNA helicase II, RHA, RNA helicase A
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rat
• Niveau de qualité: 200
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: 8E3, monoclonal
• Forme: buffered aqueous solution
• Espèces réactives: mouse, hamster, rat, bovine, canine, monkey, human
• Concentration: ~1 mg/mL
• Technique(s): immunoblotting: 1-2 μg/mL using using whole extracts of HeLa cells.; immunofluorescence: 5-10 μg/mL using using HeLa cells
• Isotype: IgG1
• Numéro d'accès UniProt: Q08211
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: Monkey ... DHX9(715453) ; canine ... DHX9(480032) ; human ... DHX9(1660) ; mouse ... Dhx9(13211) ; rat ... Dhx9(304859)

Description

Description générale

DHX9 (DEAH (Asp-Glu-Ala-His) box helicase 9) also known as RNA Helicase A, nuclear DNA helicase II (NDHII), belongs to the DExD/H family of helicase superfamily 2, that exhibits both RNA and DNA helicase activity in an ATP dependent reaction.

Immunogène

synthetic peptide corresponding to the N-terminal region of mouse DHX9

Application

Monoclonal Anti-DHX9/RHA antibody produced in rat has been used in immunoblotting and immunofluorescence.

Actions biochimiques/physiologiques

DHX9 (DEAH (Asp-Glu-Ala-His) box helicase 9) is involved in RNA metabolism including RNA secondary structure rearrangement, RNA-protein interactions, RNA turnover, ribosome biogenesis, translation and small RNA metabolism. It participates in the replication cycles of retroviruses and other RNA viruses. DHX9 is implicated in multiple steps of HIV-1 replication, including transcription, export of unspliced viral RNA from the nucleus, translation, particle assembly and reverse transcription.

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable