P4855
Poly(ADP-ribose) Polymerase Automodified bovine
solution
Synonyme(s) :
PARP
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About This Item
Numéro MDL:
Code UNSPSC :
12352203
Forme
solution
Application
Positive control for immunoblotting techniques. A streak of M.W. > 116 kDa is detected by immunoblotting, representing PARP modified to various extents by poly(ADP-ribose). Recommended use: 5-20 μl per gel lane.
Autres remarques
Partially purified bovine PARP, automodified by the addition of NAD and necessary cofactors.
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Inhibiteur
Réf. du produit
Description
Tarif
Mention d'avertissement
Danger
Mentions de danger
Conseils de prudence
Classification des risques
Acute Tox. 4 Dermal - Aquatic Chronic 3 - Eye Dam. 1 - Repr. 2 - Skin Sens. 1
Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Carla O Contreras-Ochoa et al.
Experimental parasitology, 134(2), 256-265 (2013-03-30)
Toxoplasma gondii invades any nucleated cell, but different replication speed and effects on survival/apoptosis processes have been found depending on cell type. There are scarce and controversial results regarding the effect of this parasite on host cell apoptosis within the
Wan Zhao et al.
Cancer chemotherapy and pharmacology, 71(5), 1287-1295 (2013-03-13)
Platinum-based chemotherapy is the most common treatment for patients with advanced non-small cell lung cancer (NSCLC). Genetic polymorphisms in the base excision repair (BER) pathway are suspected to influence the response of patients to this type of therapy. In this
Tomoharu Osada et al.
Biochemical and biophysical research communications, 434(1), 15-21 (2013-04-04)
We examined the roles of poly(ADP-ribosylation) in chromatin remodeling during the first cell cycle of mouse embryos. Drug-based inhibition of poly(ADP-ribosylation) by a PARP inhibitor, PJ-34, revealed up-regulation of dimethylation of histone H3 at lysine 4 in male pronuclei and
Sheng-Yi Yu et al.
Chemico-biological interactions, 203(2), 412-422 (2013-03-26)
Gefitinib, a tyrosine kinase inhibitor of the epidermal growth factor receptor (EGFR), has been used to treat numerous cancers; however, evidence has shown that cancer cells can become resistant to gefitinib during therapy. Here, we report a human proto-oncogene, securin
Karen L Cooper et al.
Toxicology and applied pharmacology, 269(2), 81-88 (2013-03-26)
Arsenic is a recognized human carcinogen and there is evidence that arsenic augments the carcinogenicity of DNA damaging agents such as ultraviolet radiation (UVR) thereby acting as a co-carcinogen. Inhibition of DNA repair is one proposed mechanism to account for
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
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