Accéder au contenu
Merck
Toutes les photos(4)

Principaux documents

N4505

Sigma-Aldrich

β-Nicotinamide adenine dinucleotide, reduced dipotassium salt

Synonyme(s) :

β-DPNH, β-NADH, DPNH, Diphosphopyridine nucleotide, reduced form, NADH

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme

Sélectionner une taille de conditionnement

100 MG
104.00 CHF
500 MG
327.00 CHF
1 G
1 070.00 CHF

104.00 CHF


Date d'expédition estimée le18 mars 2025


Devis pour commande en gros

Sélectionner une taille de conditionnement

Changer de vue
100 MG
104.00 CHF
500 MG
327.00 CHF
1 G
1 070.00 CHF

About This Item

Formule linéaire :
C21H27N7O14P2K2
Numéro CAS:
Poids moléculaire :
741.62
Numéro MDL:
Code UNSPSC :
41106305
ID de substance PubChem :
Nomenclature NACRES :
NA.51

104.00 CHF


Date d'expédition estimée le18 mars 2025


Devis pour commande en gros

Source biologique

synthetic

Niveau de qualité

Essai

≥95%

Forme

powder

Solubilité

10 mM NaOH: soluble-100 mg/mL, clear to hazy, faintly yellow to yellow

Température de stockage

−20°C

Chaîne SMILES 

[K].NC(=O)C1=CN(C=CC1)C2OC(COP(O)(=O)OP(O)(=O)OCC3OC(C(O)C3O)n4cnc5c(N)ncnc45)C(O)C2O

InChI

1S/C21H29N7O14P2.K.H/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33;;/h1,3-4,7-8,10-11,13-16,20-21,29-32H,2,5-6H2,(H2,23,33)(H,34,35)(H,36,37)(H2,22,24,25);;

Clé InChI

KMRPNNQOKAHXEZ-UHFFFAOYSA-N

Informations sur le gène

human ... IMPDH2(3615)

Application

β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).

Actions biochimiques/physiologiques

Electron donor

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number

Vous ne trouvez pas la bonne version ?

Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Luisa Schwarzmann et al.
Bioscience reports, 41(1) (2021-01-05)
Nicotinamide adenine dinucleotide (NAD) is a coenzyme in metabolic reactions and cosubstrate in signaling pathways of cells. While the intracellular function of NAD is well described, much less is known about its importance as an extracellular molecule. Moreover, there is
Cornelia Wetzker et al.
Scientific reports, 9(1), 19534-19534 (2019-12-22)
Metabolic profiles vary across all levels of biological diversity, from cells to taxa. Two-photon fluorescence lifetime imaging microscopy (FLIM) facilitates metabolic characterisation of biological specimens by assaying the intrinsic autofluorescence of the ubiquitous coenzymes NAD(P)H and FAD. The potential of
Erika Chacin et al.
Nature communications, 12(1), 5224-5224 (2021-09-03)
The replication of chromosomes during S phase is critical for cellular and organismal function. Replicative stress can result in genome instability, which is a major driver of cancer. Yet how chromatin is made accessible during eukaryotic DNA synthesis is poorly
Antonio Vassallo et al.
Pharmaceutics, 12(6) (2020-06-19)
The purpose of this study was to improve the knowledge on Hura crepitans L., a plant belonging to the Euphorbiaceae family that, on the one hand, is known to be toxic, but on the other, is a source of polyphenols
Sritama De Sarkar et al.
Parasitology research, 118(1), 335-345 (2018-11-25)
Berberine chloride, a plant-derived isoquinoline alkaloid, has been demonstrated to have leishmanicidal activity, which is mediated by generation of a redox imbalance and depolarization of the mitochondrial membrane, resulting in a caspase-independent apoptotic-like cell death. However, its impact on mitochondrial

Questions

1–4 of 4 Questions  
  1. What information do you have on the solubility and solution stability of Product N4505, β-Nicotinamide adenine dinucleotide, reduced dipotassium salt?

    1 answer
    1. Solubility and solution stability information can be found on the product information sheet (under Documents, above).

      Helpful?

  2. What is the absorption maximum and the fluorescence emission maximum wavelengths for Product N4505, β-Nicotinamide adenine dinucleotide, reduced dipotassium salt?

    1 answer
    1. The absorption maximum for NADH is at 340 nm and the fluorescence emission maximum is at 460 nm.

      Helpful?

  3. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  4. What is the extinction coefficient for Product N4505, β-Nicotinamide adenine dinucleotide, reduced dipotassium salt?

    1 answer
    1. EmM = 6.22 (340 nm) and 14.4 (259 nm, pH 9.5)

      Helpful?

Reviews

No rating value

Active Filters

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique