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M9500

Sigma-Aldrich

DL-Methionine

≥99%, suitable for cell culture and insect cell cutlure

Synonyme(s) :

(±)-2-Amino-4-(methylmercapto)butyric acid, DL-2-Amino-4-(methylthio)butanoic acid

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About This Item

Formule linéaire :
CH3SCH2CH2CH(NH2)COOH
Numéro CAS:
59-51-8
Poids moléculaire :
149.21
Beilstein:
636185
Numéro CE :
200-432-1
Numéro MDL:
MFCD00063096
Code UNSPSC :
12352209
ID de substance PubChem :
24897336
Nomenclature NACRES :
NA.26
Le tarif et la disponibilité ne sont pas disponibles actuellement.

Nom du produit

DL-Methionine, ≥99%

Essai

≥99%

Forme

powder

Technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable

Couleur

white

Pf

280 °C (dec.) (lit.)

Solubilité

H2O: soluble

Application(s)

peptide synthesis

Chaîne SMILES 

CSCCC(N)C(O)=O

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)

Clé InChI

FFEARJCKVFRZRR-UHFFFAOYSA-N

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Description générale

DL-Methionine is an essential amino acid containing sulphur.[1] Methionine consists of an asymmetric carbon and exists as D (dextrogyre) and L (levogyre) optical isomers. The L-methionine is considered as biologically active. The racemic mixture of D and L-isomers forms DL-methionine, which is the commercially available methionine.[2]

Application

DL-Methionine has been used to study its effect on the growth and feed utilization of Nile tilapia.[3] It has also been used as a part of standard diet in animal models.[4][5]

Actions biochimiques/physiologiques

DL-Methionine is an amino acid that has a role in the defence of oxidative stress.
Methionine offers protection against disorders related to hair, skin and nails. It elevates lecithin production in the liver and thereby reduces cholesterol level. It naturally serves as a heavy metal chelating agent, regulating ammonia concentration in the urine. This ameliorates bladder irritation. Methionine is also known to induce hair growth.[1]

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
WXBF4998V
WXBF1088V
WXBD7045V
WXBD8984V
WXBD6138V

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DL-Methionine sulfone ≥99.0% (NT)

Sigma-Aldrich

64410

DL-Methionine sulfone

L-Méthionine from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%

Sigma-Aldrich

M5308

L-Méthionine

L-Méthionine United States Pharmacopeia (USP) Reference Standard

USP

1411504

L-Méthionine

D-Methionine-d3 (methyl-d3) 98 atom % D

Sigma-Aldrich

589810

D-Methionine-d3 (methyl-d3)

DL-Methionine sulfoxide ≥98.5% (NT)

Sigma-Aldrich

64430

DL-Methionine sulfoxide

L-Méthionine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1241

L-Méthionine

Glucose homeostasis in mice is transglutaminase 2 independent
Iismaa SE, et al.
PLoS ONE, 8(5), e63346-e63346 (2013)
Dietary Crystalline DL-Methionine Supplementation of Oilseed Meal-Based Diets: Effects on Growth and Feed Utilization of Juvenile Nile Tilapia (Oreochromis niloticus L.)
Agbo NW, et al.
American Journal of Experimental Agriculture, 4(11), 1385-1396 (2014)
Gel growth and characterization of beta-DL-methionine
Ramachandran E and Natarajan S
Crystal Research and Technology, 41(4), 411-415 (2006)
Partial replacement of fishmeal and fish oil by algal meals in diets of red drum Sciaenops ocellatus
Perez-Velazquez M, et al.
Aquaculture (Amsterdam, Netherlands), 487, 41-50 (2018)
DL-Methionine from Methional and Hydrogen Cyanide - Cost Analysis - Methionine E11A, 6-6 (2016)
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Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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