There is no available information on the duration for which the product remains viable once reconstituted, as it was not tested for this purpose.
M3781
6α-Methylprednisolone 21-hemisuccinate sodium salt
lyophilized powder
Synonyme(s) :
6α-Methylprednisolone sodium succinate, MPSL, 6α-Methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-hemisuccinate
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25 MG
77.10 CHF
250 MG
405.00 CHF
1 G
1 260.00 CHF
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Changer de vue
25 MG
77.10 CHF
250 MG
405.00 CHF
1 G
1 260.00 CHF
About This Item
Formule linéaire :
C26H33O8Na
Numéro CAS:
Poids moléculaire :
496.53
Numéro CE :
Numéro MDL:
Code UNSPSC :
51111800
ID de substance PubChem :
Nomenclature NACRES :
NA.77
Produits recommandés
Source biologique
synthetic
Niveau de qualité
Stérilité
non-sterile
Essai
≥98.00% (TLC)
Forme
lyophilized powder
Technique(s)
toxicology assay: suitable
Solubilité
water: 50 mg/mL, clear, colorless to faintly yellow
Conditions d'expédition
ambient
Température de stockage
room temp
Chaîne SMILES
[Na+].C[C@H]1CC2C3CC[C@](O)(C(=O)COC(=O)CCC([O-])=O)[C@@]3(C)C[C@H](O)C2[C@@]4(C)C=CC(=O)C=C14
InChI
1S/C26H34O8.Na/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24;/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31);/q;+1/p-1/t14-,16-,17-,19-,23+,24-,25-,26-;/m0./s1
Clé InChI
FQISKWAFAHGMGT-SGJOWKDISA-M
Informations sur le gène
human ... NR3C1(2908)
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Application
6α-methylprednisolone 21-hemisuccinate sodium salt has been used to investigate glucocorticoid-induced osteonecrosis under hypoxic conditions in the MC3T3-E1 osteoblast cell line using a cell cytotoxicity assay, flow cytometry and western blotting.[1]
Actions biochimiques/physiologiques
Glucocorticoid with slightly longer half-life than that of prednisolone.
Forme physique
Lyophilized containing ~5% phosphate buffer salts.
Mention d'avertissement
Danger
Mentions de danger
Conseils de prudence
Classification des risques
Carc. 2 - Repr. 1B
Code de la classe de stockage
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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Les clients ont également consulté
Julio Urrutia et al.
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 16(4), 439-442 (2011-04-30)
The effect of corticosteroids on spinal fusion healing has not yet been determined. To evaluate the effect of corticosteroids on lumbar spinal fusion we designed a randomized, placebo-controlled animal study using high-dose methylprednisolone sodium succinate, which is widely used in
Acute liver failure and aplastic anemia in an 11-year-old girl.
Ann Ming Yeh et al.
Digestive diseases and sciences, 56(8), 2237-2240 (2011-03-29)
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The purpose of this study was to report a patient with acute zonal occult outer retinopathy (AZOOR) unilaterally, who received steroid pulse therapy. A 42-year-old woman presented with photopsias and severe vision loss in her left eye. Visual acuity was
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American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 69(3), 232-240 (2012-01-21)
The short-term stability of extemporaneously prepared triple intrathecal therapy, containing cytarabine, methotrexate sodium, and methylprednisolone sodium succinate, was evaluated. Three batches of triple intrathecal solution were prepared using commercially available products and stored in three different packaging materials (plastic syringe
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