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L8662

Sigma-Aldrich

L-Lysine monohydrochloride

98.5-101.0%, suitable for cell culture, non-animal source, meets EP, JP, USP testing specifications

Synonyme(s) :

(S)-2,6-Diaminohexanoic acid monohydrochloride

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About This Item

Formule linéaire :
H2N(CH2)4CH(NH2)CO2H·HCl
Numéro CAS:
657-27-2
Poids moléculaire :
182.65
Beilstein:
3563889
Numéro CE :
211-519-9
Numéro MDL:
MFCD00064564
Code UNSPSC :
12352209
ID de substance PubChem :
24896502
Nomenclature NACRES :
NA.26
Le tarif et la disponibilité ne sont pas disponibles actuellement.

Nom du produit

L-Lysine monohydrochloride, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Source biologique

non-animal source

Agence

meets EP testing specifications
meets JP testing specifications
meets USP testing specifications

Essai

98.5-101.0%

Forme

powder

Qualité

meets EP, JP, USP testing specifications

Technique(s)

cell culture | mammalian: suitable

Impuretés

endotoxin, tested

Couleur

white

Pf

263 °C (dec.) (lit.)

Solubilité

H2O: 100 mg/mL

Application(s)

pharmaceutical (small molecule)

Chaîne SMILES 

OC([C@@H](N)CCCCN)=O.[H]Cl

InChI

1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1

Clé InChI

BVHLGVCQOALMSV-JEDNCBNOSA-N

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Application


  • Scientific opinion on the presence of DNA in the feed additives consisting of concentrated liquid l-lysine, l-lysine monohydrochloride and concentrated liquid l-lysine monohydrochloride produced by Escherichia coliNITE BP-02917 for all animal species (METEX NOOVISTAGO).: This study explores the presence of DNA in l-lysine monohydrochloride and its variants used in animal feed, addressing safety concerns associated with genetic material in feed products (EFSA Panel et al., 2023).

  • Safety and efficacy of a feed additive consisting of concentrated liquid l-lysine, l-lysine monohydrochloride and concentrated liquid l-lysine monohydrochloride produced by Escherichia coliNITE BP-02917 for all animal species (Metex NoovistaGo).: Evaluates the safety and efficacy of l-lysine monohydrochloride in animal feed, contributing to a better understanding of its use and regulatory compliance (EFSA Panel et al., 2022).

  • Safety and efficacy of a feed additive consisting of l-lysine monohydrochloride and l-lysine sulfate produced by fermentation with Corynebacterium glutamicumCGMCC 17927 for all animal species (Barentz Animal Nutrition B.V.).: This publication assesses the safety and effectiveness of l-lysine monohydrochloride and l-lysine sulfate in various animal feeds, ensuring they meet health and nutritional standards (EFSA Panel et al., 2022).

  • Safety and efficacy of a feed additive consisting of l-lysine monohydrochloride and l-lysine sulfate produced by Corynebacterium glutamicum CGMCC 14498 for all animal species (Kempex Holland BV).: Investigates the implications of using l-lysine monohydrochloride and l-lysine sulfate in feed, focusing on their impact on animal health and growth (EFSA Panel et al., 2021).

  • Safety and efficacy of the feed additives concentrated liquid l-lysine (base) and l-lysine monohydrochloride produced by Corynebacterium glutamicum KCCM 80183 for all animal species (CJ Europe GmbH).: Analyzes the safety and benefits of concentrated liquid l-lysine and l-lysine monohydrochloride, detailing their advantages and regulatory approval for use in feed (EFSA Panel et al., 2021).


Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
0000419013
0000419013
0000415979
0000415980
0000415980

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Guntur Fibriansah et al.
Nature communications, 6, 6341-6341 (2015-02-24)
Dengue virus (DENV) infects ~400 million people annually. There is no licensed vaccine or therapeutic drug. Only a small fraction of the total DENV-specific antibodies in a naturally occurring dengue infection consists of highly neutralizing antibodies. Here we show that
Alexander Leitner et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(26), 9455-9460 (2014-06-19)
The study of proteins and protein complexes using chemical cross-linking followed by the MS identification of the cross-linked peptides has found increasingly widespread use in recent years. Thus far, such analyses have used almost exclusively homobifunctional, amine-reactive cross-linking reagents. Here
Chunaram Choudhary et al.
Nature reviews. Molecular cell biology, 15(8), 536-550 (2014-07-24)
Lysine acetylation is a conserved protein post-translational modification that links acetyl-coenzyme A metabolism and cellular signalling. Recent advances in the identification and quantification of lysine acetylation by mass spectrometry have increased our understanding of lysine acetylation, implicating it in many
Lunzhi Dai et al.
Nature chemical biology, 10(5), 365-370 (2014-04-01)
We report the identification of a new type of histone mark, lysine 2-hydroxyisobutyrylation (Khib), and identify the mark at 63 human and mouse histone Khib sites, including 27 unique lysine sites that are not known to be modified by lysine
Przemyslaw Nogly et al.
IUCrJ, 2(Pt 2), 168-176 (2015-04-14)
Lipidic cubic phases (LCPs) have emerged as successful matrixes for the crystallization of membrane proteins. Moreover, the viscous LCP also provides a highly effective delivery medium for serial femtosecond crystallography (SFX) at X-ray free-electron lasers (XFELs). Here, the adaptation of
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Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. Who can provide Process-Technology , Know-how and Engineering for manufacturing L-lysine Monohydrochloride from starch?

    1 answer

    1. The manufacturing processes and methods would be considered proprietary. Should you be interested in a custom quote, please navigate to the link https://www.sigmaaldrich.com/support/customer-support, click on "Quotes" under the Orders Section with all the required information so that a member of Sales team can assist.

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