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G7879

Sigma-Aldrich

D-Glucose 6-phosphate sodium salt

≥98% (HPLC)

Synonyme(s) :

D(+)-Glucopyranose 6-phosphate sodium salt, Ester de Robison, G-6-P Na

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500 MG
116.00 CHF
1 G
187.00 CHF
5 G
666.00 CHF
25 G
2 870.00 CHF

116.00 CHF

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Sélectionner une taille de conditionnement

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500 MG
116.00 CHF
1 G
187.00 CHF
5 G
666.00 CHF
25 G
2 870.00 CHF

About This Item

Formule empirique (notation de Hill) :
C6H12NaO9P
Numéro CAS:
54010-71-8
Poids moléculaire :
282.12
Beilstein:
5787568
Numéro CE :
258-921-0
Numéro MDL:
MFCD00006611
Code UNSPSC :
12352201
ID de substance PubChem :
24895324
Nomenclature NACRES :
NA.25

116.00 CHF

Check Cart for Availability
Devis pour commande en gros

Source biologique

synthetic (organic)

Niveau de qualité

300

Essai

≥98% (HPLC)

Forme

crystalline

Technique(s)

HPLC: suitable

Couleur

white

Plage de pH utile

4.0-5.0

Pf

204 °C (dec.) (lit.)

Solubilité

water: 50 mg/mL, clear, colorless to very faintly yellow

Traces de cations

Na: 6.1-10.2% (anhydrous)

Température de stockage

room temp

Chaîne SMILES 

[Na+].O[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H](O)[C@H]1O

InChI

1S/C6H13O9P.Na/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;/h2-10H,1H2,(H2,11,12,13);/q;+1/p-1/t2-,3-,4+,5-,6-;/m1./s1

Clé InChI

ZALKNDISPIVVKC-WYRLRVFGSA-M

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Catégories apparentées

Application

Le D-glucose -6-phosphate sodique peut être utilisé comme source d′énergie pour Mycobacterium tuberculoses. [1]

Actions biochimiques/physiologiques

Dans les cellules, le D-glucose 6-phosphate (G6P) est généré lorsque le glucose est phosphorylé par l′hexokinase ou la glucokinase ou par la conversion de glucose-1-phosphate par la phosphoglucomutase lors de la glycogénolyse. Le G6P se situe au début de deux voies, la glycolyse et la voie des pentoses phosphates. Il peut également être stocké sous forme de glycogène lorsque les taux sanguins en glucose sont élevés.

Attention

Non hygroscopique et très stable à l′humidité atmosphérique à température ambiante, contrairement au sel disodique.

Autres remarques

Pour bien comprendre notre vaste gamme de monosaccharides et tout ce qu'elle peut apporter à vos recherches, nous vous encourageons à visiter notre page dédiée aux glucides.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
0000436288
0000436270
0000436288
0000436270
0000365994

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Iain J Abbott et al.
Antimicrobial agents and chemotherapy, 64(6) (2020-04-08)
There are limited treatment options for enterococcal urinary tract infections, especially vancomycin-resistant Enterococcus (VRE). Oral fosfomycin is a potential option, although limited data are available guiding dosing and susceptibility. We undertook pharmacodynamic profiling of fosfomycin against E. faecalis and E.
Iain J Abbott et al.
The Journal of antimicrobial chemotherapy, 75(4), 988-996 (2019-12-25)
To assess the antibacterial effects of a single 3 g oral fosfomycin dose on Escherichia coli and Klebsiella pneumoniae clinical isolates within a dynamic bladder infection model. An in vitro model simulating dynamic urinary fosfomycin concentrations was used. Target fosfomycin exposure
Iain J Abbott et al.
Antimicrobial agents and chemotherapy, 64(3) (2020-01-08)
Oral fosfomycin trometamol is licensed as a single oral dose for the treatment of uncomplicated urinary tract infections, with activity against multidrug-resistant uropathogens. The impact of interindividual variability in urinary concentrations on antimicrobial efficacy, and any benefit of giving multiple
Iain J Abbott et al.
Journal of microbiological methods, 171, 105861-105861 (2020-02-09)
The impact of the bladder environment on fosfomycin activity and treatment response is uncertain. Standard laboratory media does not reflect the biomatrix of urine, where limited nutritional factors are important for growth and antimicrobial kill rates. We compared fosfomycin activity
Calvin S Carter et al.
Cell metabolism, 32(4), 561-574 (2020-10-08)
Aberrant redox signaling underlies the pathophysiology of many chronic metabolic diseases, including type 2 diabetes (T2D). Methodologies aimed at rebalancing systemic redox homeostasis have had limited success. A noninvasive, sustained approach would enable the long-term control of redox signaling for
Afficher tous les articles scientifiques apparentés

Articles

Aerobic Glycolysis and the Warburg Effect

Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.

Protocoles

Enzymatic Activity of Glucose-6-Phosphatase [EC 3.1.3.9]

To measure glucose-6-phosphatase activity, the Taussky-Shorr method is used. This method is a spectrophotometric stop-rate determination assay that is measured at 660 nm.

Enzymatic Assay of Glucose-6-Phosphate Dehydrogenase (EC 1.1.1.49)

To measure glucose-6-phosphate dehydrogenase activity, beta-nicotinamide adenine dinucleotide phosphate is used in a spectrophotometric rate determination assay at 340 nm.

Questions

1–3 of 3 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. May I know what is the recommended storage condition for the reconstituted working solution and the estimated shelf life for both the stock and the working solution?

    1 answer

    1. Unfortunately, the stability of the material in solution at the working concentration has not been determined. However, similar product 346764, α-D-Glucose-6-phosphate monosodium salt, states that aqueous stock solutions are stable for up to 6 weeks at -20°C.

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