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F9381

Sigma-Aldrich

Fluorometholone

≥98%

Synonyme(s) :

11β,17α-Dihydroxy-9-fluoro-6-methyl-1,4-pregnadiene-3,20-dione

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About This Item

Formule empirique (notation de Hill):
C22H29FO4
Numéro CAS:
426-13-1
Poids moléculaire :
376.46
Numéro CE :
207-041-5
Numéro MDL:
MFCD00056461
Code UNSPSC :
12352212
ID de substance PubChem :
24894996
Nomenclature NACRES :
NA.77

Pureté

≥98%

Chaîne SMILES 

C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(C)=O)[C@@]3(C)C[C@H](O)[C@]2(F)[C@@]4(C)C=CC(=O)C=C14

InChI

1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1

Clé InChI

FAOZLTXFLGPHNG-KNAQIMQKSA-N

Informations sur le gène

human ... NR3C1(2908)

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Catégories apparentées

Application


  • Topical fluorometholone treatment and desiccating stress change inflammatory protein expression in tears.: This research explores the changes in tear protein expression due to topical fluorometholone and environmental stress, offering insights into ocular surface inflammatory responses (Nättinen et al., 2018).

  • General Pharmacokinetic Model for Topically Administered Ocular Drug Dosage Forms.: This study provides a pharmacokinetic model applicable to topical ocular medications, including fluorometholone, enhancing understanding of drug dynamics in eye treatments (Deng et al., 2016).

Actions biochimiques/physiologiques

Clinically significant in allergic conjunctivitis and as anti-inflammatory following cataract surgery.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302 + H312 + H332

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Deniz Hos et al.
Archives of ophthalmology (Chicago, Ill. : 1960), 129(4), 445-452 (2011-04-13)
To analyze whether topical application of corticosteroids inhibits inflammatory corneal lymphangiogenesis and to study the potential underlying antilymphangiogenic mechanisms. Inflammatory corneal neovascularization was induced by suture placement, and the corneas were then treated with topical fluorometholone, prednisolone acetate, or dexamethasone
Alejandro Portero et al.
Cornea, 32(2), 161-164 (2012-06-08)
Hairs from the caterpillar of the pine processionary moth, Thaumetopoea pityocampa, located in the pine forests of southern Europe and elsewhere, can become embedded in the cornea and conjunctiva. Disorders produced by the urticating hairs can be classified into a
Kaevalin Lekhanont et al.
Cornea, 31(2), 155-161 (2011-11-15)
To investigate the efficacy and safety of subconjunctival bevacizumab injection for the treatment of impending recurrent pterygium. A prospective, randomized, single-masked, controlled trial was conducted in 80 patients with impending recurrent pterygium. Patients were randomized into 4 groups using random
Miguel Naveiras et al.
American journal of ophthalmology, 153(5), 958-966 (2012-01-31)
To describe the incidence and causes of glaucoma after Descemet membrane endothelial keratoplasty (DMEK). Nonrandomized prospective cohort study at a tertiary referral center. The incidence of glaucoma was evaluated in the first 275 consecutive eyes that underwent DMEK for Fuchs
Brett W Davies et al.
Archives of ophthalmology (Chicago, Ill. : 1960), 129(7), 909-913 (2011-07-13)
To compare topical interleukin 1 receptor antagonist (IL-1ra) to steroid treatment following photorefractive keratectomy (PRK) in rabbit eyes. Our study is a randomized, investigator-masked study that was approved by the Institutional Animal Care and Use Committee. Following standard PRK, 48
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