Accéder au contenu
Merck
Toutes les photos(3)

Principaux documents

Voir toute la documentation

E6758

Sigma-Aldrich

Ethylenediaminetetraacetic acid

anhydrous, crystalline, BioReagent, suitable for cell culture

Synonyme(s) :

(Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme

Sélectionner une taille de conditionnement

100 G
65.70 CHF
500 G
246.00 CHF

65.70 CHF

Date d'expédition estimée le22 mars 2025

Devis pour commande en gros
Toutes les photos(3)

Sélectionner une taille de conditionnement

Changer de vue
100 G
65.70 CHF
500 G
246.00 CHF

About This Item

Formule linéaire :
(HO2CCH2)2NCH2CH2N(CH2CO2H)2
Numéro CAS:
60-00-4
Poids moléculaire :
292.24
Beilstein:
1716295
Numéro CE :
200-449-4
Numéro MDL:
MFCD00003541
Code UNSPSC :
12161700
eCl@ss :
39030907
ID de substance PubChem :
24894634
Nomenclature NACRES :
NA.25

65.70 CHF

Date d'expédition estimée le22 mars 2025

Devis pour commande en gros

Qualité

anhydrous

Niveau de qualité

200

Gamme de produits

BioReagent

Essai

≥98.5%

Forme

crystalline

Pertinence de la réaction

reagent type: chelator

Technique(s)

cell culture | mammalian: suitable

pH

2.5 (23 °C, 10 g/L)

Pf

250 °C (dec.) (lit.)

Solubilité

3  M NaOH: 100 mg/mL

Densité

1.46 g/cm3 at 20 °C

Traces de cations

C: 40.7-41.5%
N: 9.3-9.8%

Chaîne SMILES 

OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

InChI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

Clé InChI

KCXVZYZYPLLWCC-UHFFFAOYSA-N

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Application

Ethylenediaminetetraacetic acid has been used:
  • as a component of peptide dilution buffer for intracellular BH3 (Bcl-2 homology (BH) domain) profiling and validation[1]
  • as a medium component in the hepatic stellate cell (HSCs) culture[2]
  • as a component of homogenization buffer for protein extraction from eye tissues[3]
  • for stopping benzonase reaction in lysis buffer[4]

Actions biochimiques/physiologiques

Ethylenediaminetetraacetic acid (EDTA) is an anticoagulant, majorly used in preventing clotting of blood samples.[5] EDTA may trigger aggregation of platelets resulting in pseudothrombocytopenia.[6] EDTA along with tetracycline imparts serves as root conditioning agent and provides relief in gum infection.[5] EDTA-tetracycline therapy decreases coronary artery calcium levels in atherosclerosis.[7] Calcium Disodium EDTA administration is effective in slowing down the progression of chronic kidney disease.[8]

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H319

Classification des risques

Eye Irrit. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
0000410021
0000410021
0000410023
0000410023
0000405110

Vous ne trouvez pas la bonne version ?

Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.

Rechercher un(e) COA

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Analysis of Direct Interaction between Viral DNA-binding Proteins by Protein Pull-down Co-immunoprecipitation Assay
Lechuga A, et al.
Bio-protocol, 8(1), 1571-1571 (2018)
Intracellular BH3 Profiling Reveals Shifts in Antiapoptotic Dependency in Human B Cell Maturation and Mitogen-Stimulated Proliferation
Dai J and Luftig MA
Journal of Immunology, ji1701473-ji1701473 (2018)
The blockade of lipophagy pathway is necessary for docosahexaenoic acid to regulate lipid droplet turnover in hepatic stellate cells
Qiu S, et al.
Biomedicine and Pharmacotherapy, 109, 1841-1850 (2019)
Protein Expressions of the Small GTPase Rho Proteins in Pterygial Tissue and Leukocytes of Patients with Pterygium
Saracaloglu A, et al.
Proceedings, 2(25), 1571-1571 (2018)
Comparison of the efficacy of ethylenediaminetetraacetic acid and tetracycline hydrochloride as root conditioning agents: An in vitro study
Nanda T, et al.
Journal of the International Clinical Dental Research Organization, 4(1), 2-2 (2012)
Afficher tous les articles scientifiques apparentés

Protocoles

Restriction Enzyme Cloning Manual Buffer Recipes

TE Buffer; Elution Buffer; 10x Ligation Buffer; 0.5 M PIPES Buffer; Inoue Transformation Buffer

Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

Reviews

No rating value

Active Filters

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique