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C7519

Sigma-Aldrich

Choline bicarbonate

~80% in H2O

Synonyme(s) :

2-Hydroxyethyl)trimethylammonium bicarbonate

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About This Item

Formule linéaire :
C5H14NO · HCO3
Numéro CAS:
78-73-9
Poids moléculaire :
165.19
Numéro MDL:
MFCD00031689
Code UNSPSC :
50501514
ID de substance PubChem :
24892967
Nomenclature NACRES :
NA.25

Forme

liquid

Concentration

~80% in H2O

Densité

1.17 g/mL at 25 °C (lit.)

Type de lipide

phospholipids

Température de stockage

2-8°C

Chaîne SMILES 

OC([O-])=O.C[N+](C)(C)CCO

InChI

1S/C5H14NO.CH2O3/c1-6(2,3)4-5-7;2-1(3)4/h7H,4-5H2,1-3H3;(H2,2,3,4)/q+1;/p-1

Clé InChI

DQKGOGJIOHUEGK-UHFFFAOYSA-M

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Application

Choline, a water soluble essential nutrient, is used by the body to make phosphatidylcholine phosphatides and neurotransmitter such as acetylcholine. Choline is used to study a wide range of biological processes from stem cell development to neurological disease studies. Also, An alkaline intermediate useful for preparing salts.

Actions biochimiques/physiologiques

Acyl group acceptor

Substrats

Choline acetyltransferase substrate

Autres remarques

Note: The bicarbonate converts to the carbonate with release of CO2 on aging.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319,H335

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Fred Elhi et al.
Molecules (Basel, Switzerland), 25(7) (2020-04-11)
Mixing ionic liquids is a suitable strategy to tailor properties, e.g., to reduce melting points. The present study aims to widen the application range of low-toxic choline-based ionic liquids by studying eight binary phase diagrams of six different choline carboxylates.
Diana Gómora-Herrera et al.
Applied spectroscopy, 72(4), 562-572 (2017-12-09)
The effects exerted by the adsorption of vapors of a non-polar compound (deuterated benzene) and a polar compound (water) on the surface of Ottawa sand and a sample of reservoir sand (Channel), which was previously impregnated with silicon oil or
Eden E L Tanner et al.
Journal of controlled release : official journal of the Controlled Release Society, 286, 137-144 (2018-07-22)
Transdermal delivery of pharmaceuticals using ionic liquids and deep eutectic solvents (DES) has attracted significant interest due to the inherent tunability of the molecules and their capacity to transport large molecules across the skin. Several key properties of DESs including
Vimisha Dharamdasani et al.
Journal of controlled release : official journal of the Controlled Release Society, 323, 475-482 (2020-04-28)
Skin diseases such as lupus, cancer, psoriasis, and hyperhidrosis can potentially be treated effectively by suppressing allele-specific genes using small interfering RNA (siRNA). Injections of siRNA into skin, though effective, are painful and cover small surface areas and thus are
Hussain Mohamad Awwad et al.
Clinical biochemistry, 45(18), 1548-1553 (2012-08-28)
Choline is an essential nutrient that is necessary for cell membrane synthesis and phospholipid metabolism and functions as an important methyl donor. Multiple roles for choline in cancer development have been suggested. Choline can affect DNA methylation and lead to
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