C6737

Chondroitin sulfate sodium salt from bovine cartilage

98-102% (CPC, titration)

• Numéro CAS: 9082-07-9
• Code UNSPSC : 12352201
• ID de substance PubChem : 24892886
• Nomenclature NACRES : NA.25

Propriétés

• Source biologique: bovine cartilage
• Qualité: standard (for CPC (cetylpyridinium chloride) titration)
• Essai: 98-102% (CPC, titration)
• Forme: powder
• Activité optique: [α]20/D -30 to -20 °, c = 5% (w/v) in water
• Impuretés: <10.0% water (Karl Fischer)
• Couleur: white to off-white
• Solubilité: H₂O: soluble 50 mg/mL, clear to hazy, colorless to faintly yellow
• Traces de cations: Na: 7.4-8.8% (anhydrous)
• Température de stockage: 2-8°C
• Chaîne SMILES: [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]2O[C@@H]([C@H](O)[C@@H](O)[C@@H]2O)C(O)=O
• InChI: 1S/C14H23NO15S.Na/c1-3(17)15-5-10(9(30-31(24,25)26)4(2-16)27-13(5)23)28-14-8(20)6(18)7(19)11(29-14)12(21)22;/h4-11,13-14,16,18-20,23H,2H2,1H3,(H,15,17)(H,21,22)(H,24,25,26);/q;+1/p-1/t4-,5-,6-,7-,8+,9+,10-,11+,13-,14+;/m1./s1
• Clé InChI: SHQAYVXGAAXVHV-GNAIRZFJSA-M

Description

Description générale

Chondroitin, a glucosaminoglycan (GAG), is a polysaccharide chain of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA) that can be sulfated on the either or both GalNAc and GlcA units. Chondroitin and its sulfates are frequently attached to proteins to form proteoglycans.[1]

Application

Chondroitin sulfate, a glucosaminoglycan (GAG) polysaccharide chain of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA), is used in a wide variety of areas of research including bioengineering. Chondroitin sulfate may be used as a biomaterial copolymer or surface derivatization reagent in the development of drug delivery vehicles, tissue engineering devices and bioscaffolds. Chondroitin sulfate may be used for the development of biocompatible structures such as hydrogels, sponges, biofilms, microspheres and micelles.[2]

Actions biochimiques/physiologiques

As a large, negatively charged, hydrophilic molecule that is too inflexible to fold into a compact globular structure, chondroitin sulfate molecules form porous hydrated gels, providing mechanical support to tissue and allowing rapid diffusion of water-soluble molecules and migration of cells.

Composants

Chondroitin is an acidic mucopolysaccharide found in cartilage, skin, cornea, and umbilical cord. It is composed of alternating N-acetylgalactosamine, D-glucuronic acid, and sulfate residues in equimolar quantities that can be sulfated on either of its subunits. Sulfation can occur at the 6 and/or 4-position of the galactosamine moiety, with potential for any individual disaccharide unit to be 6-sulfated, 4-sulfated, 4,6-disulfated, or unsulfated.

Attention

Store this product at 2-8°C.

Notes préparatoires

This product is soluble in water at 100 mg/mL.

Autres remarques

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Informations sur la sécurité

• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)