B3251 is a laboratory research grade product. It has two purity specifications, Titration by perchloric acid with a purity specification of 97 - 102 % and a TLC purity with a specification of ≥ 98 %. The CAS number for B3251 - Berberine chloride form is synonymous with Benzodioxide, Berberine HCl, Natural Yellow 18.
B3251
Berberine chloride form
Synonyme(s) :
Benzodioxide, Berberine HCl, Natural Yellow 18
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Sélectionner une taille de conditionnement
5 G
67.60 CHF
10 G
132.00 CHF
25 G
274.00 CHF
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Changer de vue
5 G
67.60 CHF
10 G
132.00 CHF
25 G
274.00 CHF
About This Item
Formule empirique (notation de Hill):
C20H18ClNO4
Numéro CAS:
Poids moléculaire :
371.81
Numéro C.I. (Colour Index):
75160
Beilstein:
3836585
Numéro CE :
Numéro MDL:
Code UNSPSC :
12171500
ID de substance PubChem :
Nomenclature NACRES :
NA.32
Produits recommandés
Forme
powder
Niveau de qualité
Solubilité
methanol: soluble
Chaîne SMILES
COC1=C(C=[N+](CCC2=C3C=C4C(OCO4)=C2)C3=C5)C5=CC=C1OC.[Cl-]
InChI
1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1
Clé InChI
VKJGBAJNNALVAV-UHFFFAOYSA-M
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Description générale
Berberine Chloride form or Natural Yellow 18, is also known as 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo (5,6-a) quinolizinium is a benzyl tetra isoquinoline plant alkaloid. Berberine contains a quaternary base and is commercially available in berberine chloride form.
Application
Berberine Chloride is a fluorescent stain used to stain heparin in mast cells. Berberine upregulates the expression of Pgp in hepatoma cells.
Fluorescent stain for heparin in mast cells
Actions biochimiques/physiologiques
An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5´-methoxyhydnocarpin (5´-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
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Conjugation of the NorA substrate berberine and the NorA inhibitor 5-nitro-2-phenyl-1H-indole via a methylene ether linking group gave the 13-substituted berberine-NorA inhibitor hybrid, 3. A series of simpler arylmethyl ether hybrid structures were also synthesized. The hybrid 3 showed excellent
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A series of 9-N-substituted berberine derivatives (2a-j) were synthesized and evaluated as a new class of G-quadruplex binding ligands. G-quadruplex of DNA had been proven to be the transcription controller of human c-myc gene. The interaction of 9-N-substituted berberine derivatives
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Journal of medicinal chemistry, 52(2), 492-501 (2008-12-19)
Twenty-nine derivatives of berberine (1) or pseudoberberine (2) were designed, semisynthesized, and evaluated for their up-regulatory activity on the low-density-lipoprotein receptor (LDLR) expression. SAR analysis revealed that (i) the methylenedioxy group at the 2- and 3-position is an essential element
Articles
Protein-based drug transporters are expressed in Sf9 cells. Understanding the specific mechanisms of tumor cell transporters is an essential aspect of chemotherapeutic drug design.
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I want to ask you about this compound whether it is API. And what is the purity percentage. Further. I want to inquire about this compound. Is it same berberine hydrochloride
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