B0385

Beclomethasone

≥99%

• Synonyme(s) : 9α-Chloro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione, 9α-Chloro-16β-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione
• Formule empirique (notation de Hill) : C₂₂H₂₉ClO₅
• Numéro CAS: 4419-39-0
• Poids moléculaire : 408.92
• Numéro CE : 224-585-9
• Numéro MDL: MFCD00135614
• Code UNSPSC : 12352200
• ID de substance PubChem : 24278253
• Nomenclature NACRES : NA.77

Propriétés

• Essai: ≥99%
• Forme: powder
• Auteur: GlaxoSmithKline
• Température de stockage: 2-8°C
• Chaîne SMILES: [H][C@]12C[C@@H](C)[C@@](O)(C(=O)CO)[C@]1(C)C[C@@H](O)[C@@]3(Cl)[C@]2([H])CCC4=CC(=O)C=C[C@@]34C
• InChI: 1S/C22H29ClO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12?,15?,16?,17?,19?,20?,21-,22?/m0/s1
• Clé InChI: NBMKJKDGKREAPL-WOOYFSPWSA-N
• Informations sur le gène: human ... CYP1A2(1544)

Description

Application

Beclomethasone has been used in MS−MS (mass spectrometry) methods for the analysis of β-agonists, corticosteroids, chloramphenicol and penicillins.[1] It has also been used to find the differential response of glucocorticoids in larval regeneration model.[2]

Actions biochimiques/physiologiques

Beclomethasone is an anti-inflammatory glucocorticoid.
It helps to decrease airway hyperresponsiveness. It also helps to regulate symptoms of asthma.[3]

Caractéristiques et avantages

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)