A6779

Adenosine 5′-triphosphate, periodate oxidized sodium salt

≥97%

• Synonyme(s) : oATP, Adenosine 5′-triphosphate-2′,3′-dialdehyde
• Formule empirique (notation de Hill) : C₁₀H₁₄N₅O₁₃P₃
• Numéro CAS: 71997-40-5
• Poids moléculaire : 505.17
• Numéro MDL: MFCD00056956
• Code UNSPSC : 41106305
• eCl@ss : 32160414
• ID de substance PubChem : 24891137
• Nomenclature NACRES : NA.51

Propriétés

• Source biologique: bacterial (corynebacterium sp)
• Essai: ≥97%
• Forme: powder
• Température de stockage: −20°C
• Chaîne SMILES: [Na].Nc1ncnc2n(cnc12)[C@H](O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C=O)C=O
• InChI: 1S/C10H14N5O13P3.Na.H/c11-9-8-10(13-4-12-9)15(5-14-8)7(2-17)26-6(1-16)3-25-30(21,22)28-31(23,24)27-29(18,19)20;;/h1-2,4-7H,3H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;/t6-,7+;;/m0../s1
• Clé InChI: IHQATUPGVKMGLT-AUCRBCQYSA-N

Description

Description générale

Adenosine 5′-triphosphate 2′,3′ dialdehyde is a derivative of dialdehyde.[1]

Application

Adenosine 5′-triphosphate, periodate oxidized sodium salt has been used:

• as an antagonist of the purinergic receptor, P2 × 7 to inhibit P2 × 7 pathway[2]
• as a nonspecific agonist to assess the activity of P2×₇-R by the mobilization of Ca²⁺[3]
• to evaluate the physiological significance of elevated intracellular ATP levels
• increased P2rx7 expression for osteoclastogenesis in Flcn-deficient cells[4]

Actions biochimiques/physiologiques

Adenosine 5′-triphosphate 2′,3′ dialdehyde is considered as an inhibitor of P2 × 7 receptor.[2]

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)