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Principaux documents

48165

Sigma-Aldrich

Chitosan from crab shells

highly viscous

Synonyme(s) :

2-Amino-2-deoxy-(1→4)-β-D-glucopyranan, Poly-(1,4-β-D-glucopyranosamine)

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About This Item

Numéro CAS:
Numéro MDL:
Code UNSPSC :
12352201
Nomenclature NACRES :
NA.25

Source biologique

(crab)

Forme

powder

Impuretés

≤1% insoluble matter

Résidus de calcination

≤2% (as SO4)

Perte

≤12% loss on drying

Couleur

yellow

Viscosité

>400 mPa.s, 1 % in acetic acid(20 °C)

InChI

1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1

Clé InChI

FLASNYPZGWUPSU-SICDJOISSA-N

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Description générale

Chitosan is a linear amino polysaccharide composed of approximately 20% β1,4-linked N-acetyl-D-glucosamine (GlcNAc) and approximately 80% β1,4-linked D-glucosamine (GlcN) that is prepared by the partial deacetylation of chitin in hot alkali.

Application

Chitosan is a biocompatible, antibacterial, and biodegradable polyelectrolyte with a variety of industrial and biomedical applications. Its chemical properties and low toxicity make it particularly suitable as a component of drug and gene delivery systems, and for the development of biodegradable films and scaffolds for tissue engineering.

Autres remarques

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Kyriaki G Zinoviadou et al.
Food & function, 3(3), 312-319 (2012-02-03)
Oil-in-water emulsions (10% w/w n-tetradecane) were prepared at pH = 5.7 by using, as surface active agents, electrostatically formed complexes of sodium stearoyl lactylate (SSL) at a concentration of 0.4% (w/w) and chitosan (CH) in a concentration range between 0
Rushita Shah et al.
Polymers, 11(12) (2019-12-19)
The application of polymeric biomaterial scaffolds utilizing crosslinking strategy has become an effective approach in these days. In the present study, the development and characterization of collagen-chitosan hydrogel film has been reported on using dual crosslinking agent's, i.e., tannic acid
Liming Hu et al.
Nanoscale, 5(8), 3103-3111 (2013-03-22)
Within the past few years, chitosan-based drug delivery vehicles have become some of the most attractive to be studied. In contrast to all other polysaccharides, chitosan has demonstrated its unique characteristics for drug delivery platforms, including its active primary amino
William D Stanish et al.
The Journal of bone and joint surgery. American volume, 95(18), 1640-1650 (2013-09-21)
Microfracture, the standard of care, is recognized to be an incomplete solution for cartilage damage. BST-CarGel, a chitosan-based medical device, is mixed with autologous whole blood and is applied to a microfractured cartilage lesion in which it physically stabilizes the
Bijay Singh et al.
Journal of nanoscience and nanotechnology, 14(1), 564-576 (2014-04-16)
Successful gene therapy depends on the development of efficient and cell-specific gene delivery systems. Currently, animal viral vectors have been mostly used for in vivo and in clinical trials owing to their high transduction efficiency. However, they suffer from numerous

Questions

1–3 of 3 Questions  
  1. What is the degree of deacetylation of this reagent?

    1 answer
    1. The degree of acetylation should be above 75% for each lot, but the exact value will vary. For information on the degree of acetylation for a particular lot, contact the local technical service team.

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  2. What is the molecular weight of this chitosan (ref 48165)?

    1 answer
    1. The molecular weight for this product is not analyzed on a lot to lot basis. However, the expected range is 500,000 to 700,000 g/mol.

      Helpful?

  3. Greetings I wish to know if this chitosan is soluble or insoluble in water. I also realized that there is water-soluble chitosan. Please kindly clarify the difference. I need them to do laboratory experiments.

    1 answer
    1. This product has not been tested for it's solubility in water. However, one gram chitosan can be dissolved in a mixture of 100mL 10% acetic acid and 50mL methanol, and then precipitated from a precipitant consisted of 10mL ethanol and 90mL acetate ester. The treated chitosan should become soluble in acid-free water completely at 8.02mg/mL

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