478M-9

CDK4 (DCS-31) Mouse Monoclonal Antibody

• Code UNSPSC : 12352203

Propriétés

• Source biologique: mouse
• Niveau de qualité: 100; 500
• Conjugué: unconjugated
• Forme d'anticorps: culture supernatant
• Type de produit anticorps: primary antibodies
• Clone: DCS-31, monoclonal
• Description: For In Vitro Diagnostic Use in Select Regions
• Forme: buffered aqueous solution
• Espèces réactives: human
• Conditionnement: vial of 0.1 mL concentrate (478M-94); vial of 0.1 mL concentrate Research Use Only (478M-94-RUO); vial of 0.5 mL concentrate (478M-95); vial of 1.0 mL concentrate (478M-96); vial of 1.0 mL concentrate Research Use Only (478M-96-RUO); vial of 1.0 mL pre-dilute Research Use Only (478M-97-RUO); vial of 1.0 mL pre-dilute ready-to-use (478M-97); vial of 7.0 mL pre-dilute ready-to-use (478M-98); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (478M-98-RUO)
• Fabricant/nom de marque: Cell Marque^®
• Technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:50 (concentrated)
• Isotype: IgG
• Contrôle: dedifferentiated liposarcoma, well-differentiated liposarcoma
• Conditions d'expédition: wet ice
• Température de stockage: 2-8°C
• Visualisation: nuclear

Description

Description générale

Well-differentiated liposarcoma is a malignant, non-metastasizing tumor that can present with similar histological characteristics as benign lipoma lesions and has a higher recurrence rate. The CDK4 protein is frequently overexpressed in well-differentiated liposarcoma due to gene amplification of the 12q13-15 chromosomal region that harbors the CDK4 gene, but amplification and subsequent overexpression is rarely observed in lipomas. Due to CDK4 protein expression differences between these lesions, anti-CDK4 antibody can be used in an immunohistochemistry panel as an aid in the differential diagnosis between well-differentiated liposarcoma and lipoma.^1,2,3

Qualité

United States - IVD
Canada - RUO
European Union - IVD
Japan - RUO

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Notes préparatoires

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Autres remarques

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Informations légales

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany