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02071

Sigma-Aldrich

Catalase from Corynebacterium glutamicum

solution, deep brown, ≥500000 U/mL

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218.00 CHF

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1 ML
62.40 CHF
5 ML
218.00 CHF

About This Item

Numéro CAS:
Numéro de classification (Commission des enzymes):
Numéro MDL:
Code UNSPSC :
12352204
Nomenclature NACRES :
NA.54

62.40 CHF


Check Cart for Availability
Les fabricants de produits de diagnostic devraient utiliser un produit d'une autre qualité : SRE0041

Devis pour commande en gros

Source biologique

bacterial (Corynebacterium glutamicum)

Forme

solution

Concentration

≥500000 U/mL

Couleur

deep brown

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Chaîne SMILES 

O(CC)C(=O)c1ccc(cc1)O

InChI

1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3

Clé InChI

NUVBSKCKDOMJSU-UHFFFAOYSA-N

Description générale

Catalase is ubiquitously found in animals, plants, fungi, and humans. It is made up of looped polypeptide chains that are arranged as tetramers or dimers and a core, that contains iron or manganese ions. Catalase can be differentiated into two types such as heme-containing (type I), which possesses an iron-porphyrin cofactor and a non-heme-containing (type II), which possesses a dinuclear manganese active site.

Application

Catalase from Corynebacterium glutamicum has been used to identify and characterize purified bacterial peptide (PPBP) produced from Bacillus thuringiensis. It has also been used to study its inhibition by nitric oxide.

Actions biochimiques/physiologiques

Catalase is an antioxidant enzyme that plays a role in alleviating oxidative stress by the removal of hydrogen peroxide to produce oxygen and water. Lower levels of catalase lead to several age-related disorders including hypertension, anemia, vitiligo, Parkinson′s disease, Alzheimer′s disease, schizophrenia, bipolar disorders, diabetes mellitus, and cancer.

Définition de l'unité

1 U corresponds to the amount of enzyme which decomposes 1 μmol H2O2 per minute at pH 7.0 and 25°C

Forme physique

contains ~30% glycerol, 10% ethanol

Autres remarques

The purity of this product is not determined. It is tested and sold by activity rather than mass.

Pictogrammes

Flame

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Flam. Liq. 3

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

105.8 °F - closed cup

Point d'éclair (°C)

41 °C - closed cup

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Nitin Kumar et al.
Science advances, 4(10), eaat7779-eaat7779 (2018-10-20)
Active materials are capable of converting free energy into directional motion, giving rise to notable dynamical phenomena. Developing a general understanding of their structure in relation to the underlying nonequilibrium physics would provide a route toward control of their dynamic
Milka O Montes et al.
International journal of phytoremediation, 15(2), 168-187 (2013-03-16)
Hexavalent chromium is a contaminant highly mobile in the environment that is toxic for plants at low concentrations. In this work, the physiological response of Convolvulus arvensis and Medicago truncatula plants to Cr(VI) treatments was compared. C. arvensis is a
A E Kratnov
Klinicheskaia laboratornaia diagnostika, (12)(12), 10-12 (2013-03-14)
The article deals with the results of study of the intracellular metabolism of neutrophils in 96 patients including 56 (58.3%) patients with ischemic heart disease. It is established that in patients with ischemic heart disease as compared with patients without
Maryam Sharifi-Sanjani et al.
American journal of physiology. Heart and circulatory physiology, 304(10), H1294-H1301 (2013-03-26)
Myocardial metabolites such as adenosine mediate reactive hyperemia, in part, by activating ATP-dependent K(+) (K(ATP)) channels in coronary smooth muscle. In this study, we investigated the role of adenosine A(2A) and A(2B) receptors and their signaling mechanisms in reactive hyperemia.
Dusan Sokolovic et al.
General physiology and biophysics, 32(1), 79-90 (2013-03-28)
The aim of the study was to evaluate the effect of melatonin on oxidative stress, DNA fragmentation, apoptsis and proliferation in thymus tissue of rats exposed to microwaves. Wistar rats were divided in four groups: I - treated with saline;

Questions

  1. What is the concentration and purity of the catalase?

    1 answer
    1. The purity of this product is not determined. It is tested and sold by activity rather than mass. The lot specific activity is reported in units per mL and can be found in the Certificate of Analysis. Please see the link below for sample Certificate of Analysis:
      https://www.sigmaaldrich.com/certificates/Graphics/COfAInfo/fluka/pdf/PDF736758.pdf

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