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Y0001510

Lactulose for peak identification

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Lactulose, 4-O-β-D-Galactopyranosyl-D-fructofuranose, 4-O-β-D-Galactopyranosyl-D-fructose

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About This Item

Formule empirique (notation de Hill):
C12H22O11
Numéro CAS:
4618-18-2
Poids moléculaire :
342.30
Numéro Beilstein :
93773
Numéro MDL:
MFCD00151469
Code UNSPSC :
41116107
ID de substance PubChem :
329831465
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

lactulose

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)O[C@@](O)(CO)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C12H22O11/c13-1-4-6(16)7(17)8(18)11(21-4)22-9-5(2-14)23-12(20,3-15)10(9)19/h4-11,13-20H,1-3H2/t4-,5-,6+,7+,8-,9-,10+,11+,12+/m1/s1

Clé InChI

JCQLYHFGKNRPGE-WJONTELPSA-N

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lactulose for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Amit Maydeo
Journal of the Indian Medical Association, 108(11), 789-792 (2011-04-23)
Constipation is a common problem for adults and paediatric patients and can generate considerable suffering for patients due to both the unpleasant physical symptoms and psychological preoccupations that can arise. Since disaccharide sugar is widely prescribed osmotic laxative in India
H Huchzermeyer et al.
Zeitschrift fur Gastroenterologie, 35(10), 945-955 (1997-11-25)
Lactulose is therapeutically used in hepatic encephalopathy, constipation, and salmonellosis. This semisynthetic disaccharide is neither metabolized nor absorbed in the normal small intestines. Comparable to plant-polysaccharides lactulose is bacterially fermented in the colon to short chain fatty acids and gases.
[The lactulose challenge--history and future of a drug].
C Schumann
Zeitschrift fur arztliche Fortbildung, 88(5-6), 403-411 (1994-06-01)
He Wang et al.
Applied microbiology and biotechnology, 97(14), 6167-6180 (2013-06-19)
Lactulose, a synthetic ketose disaccharide, has been widely used in food and pharmaceutical industries as prebiotic food additives and drugs against constipation and hepatic encephalopathy. Lactulose has, so far, been produced chemically using lactose on a commercial scale. The key
G P VanBerge-Henegouwen et al.
Scandinavian journal of gastroenterology. Supplement, 222, 68-71 (1997-01-01)
The primum movens in cholesterol gallstone formation is hepatic cholesterol hypersecretion and chronic supersaturation of bile. From this event a cascade of contributing factors can be differentiated: (i) Motility defects with impaired gallbladder contractility and gallbladder stasis, but also with
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