F6145

Fenspiride hydrochloride

analytical standard, for drug analysis

• Synonyme(s) : 8-(2-Phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride
• Formule empirique (notation de Hill) : C₁₅H₂₀N₂O₂ · HCl
• Numéro CAS: 5053-08-7
• Poids moléculaire : 296.79
• Numéro CE : 225-752-9
• Numéro MDL: MFCD00133315
• Code UNSPSC : 41116107
• ID de substance PubChem : 329799751

Propriétés

• Qualité: analytical standard
• Niveau de qualité: 200
• Essai: >99% (TLC)
• Forme: powder
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Couleur: white
• Application(s): forensics and toxicology; pharmaceutical (small molecule); veterinary
• Format: neat
• Chaîne SMILES: Cl.O=C1NCC2(CCN(CCc3ccccc3)CC2)O1
• InChI: 1S/C15H20N2O2.ClH/c18-14-16-12-15(19-14)7-10-17(11-8-15)9-6-13-4-2-1-3-5-13;/h1-5H,6-12H2,(H,16,18);1H
• Clé InChI: FIKFLLIUPUVONI-UHFFFAOYSA-N
• Informations sur le gène: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , HRH1(3269)

Description

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Actions biochimiques/physiologiques

Bronchodilator with anti-inflammatory properties. Inhibits mucus secretion and reduces the release of tachykinins at a prejunctional level by its anti-muscarinic action. It also may be an antagonist at α adrenergic and H₁ histamine receptors.

Bronchodilator with anti-inflammatory properties. Inhibits mucus secretion and reduces the release of tachykinins at a prejunctional level by its anti-muscarinic action. It also may be an antagonist at α adrenergic and H₁ histamine receptors.
Fenspiride hydrochloride possesses anti-allergic and anti-bronchoconstrictive properties. It is used as a drug to treat inflammatory conditions of the upper and lower respiratory tracts.[1] Experimental studies state that fenspiride has an ability to reduce the development of myringosclerosis, possibly by restricting the formation of oxygen-derived free radicals.[1]

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302 + H312 + H332
• Conseils de prudence: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Classification des risques: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Faceshields, Gloves