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F0048010

Fenofibrate impurity B

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic acid, Fenofibric acid

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About This Item

Formule empirique (notation de Hill):
C17H15ClO4
Numéro CAS:
42017-89-0
Poids moléculaire :
318.75
Numéro Beilstein :
2058973
Numéro MDL:
MFCD00792461
Code UNSPSC :
41116107
ID de substance PubChem :
329799626
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

fenofibrate

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

O=C(C1=CC=C(OC(C)(C)C(O)=O)C=C1)C2=CC=C(Cl)C=C2

InChI

1S/C17H15ClO4/c1-17(2,16(20)21)22-14-9-5-12(6-10-14)15(19)11-3-7-13(18)8-4-11/h3-10H,1-2H3,(H,20,21)

Clé InChI

MQOBSOSZFYZQOK-UHFFFAOYSA-N

Informations sur le gène

human ... PPARA(5465)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Fenofibrate impurity B EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

1269447

Fenofibrate, United States Pharmacopeia (USP) Reference Standard

F0048005

Fenofibrate impurity A, European Pharmacopoeia (EP) Reference Standard

1269607

Fenofibrate Related Compound A, United States Pharmacopeia (USP) Reference Standard

1269629

Fenofibrate Related Compound C, United States Pharmacopeia (USP) Reference Standard

1269618

Fenofibrate Related Compound B, United States Pharmacopeia (USP) Reference Standard

F0048035

Fenofibrate impurity G, European Pharmacopoeia (EP) Reference Standard

PHR1246

Fenofibrate, Pharmaceutical Secondary Standard; Certified Reference Material

1133558

Choline Fenofibrate, United States Pharmacopeia (USP) Reference Standard

PHR2864

Fenofibrate Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

Pictogrammes

Exclamation markEnvironment
GHS07,GHS09

Mention d'avertissement

Warning

Mentions de danger

H302,H410

Classification des risques

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Inactivation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in cultured human blood mononuclear cells by procetofenic acid.
C Massaroli et al.
Pharmacological research communications, 14(1), 51-60 (1982-01-01)
Rapid determination of procetofenic acid in plasma by high-performance liquid chromatography.
M C Caturla et al.
Journal of chromatography, 227(1), 219-222 (1982-01-08)
Simple and rapid method for determining procetofenic acid, an active metabolite of procetofen, in biological fluids by solid-phase extraction and high-performance liquid chromatography.
A C Ramusino et al.
Journal of chromatography, 383(2), 419-424 (1986-12-19)
R Aldini et al.
British journal of pharmacology, 74(3), 611-617 (1981-11-01)
1 Hypolipidaemic agents may increase biliary cholesterol in man, inducing a supersaturated bile. 2 To evaluate this possible side-effect, we have studied bile lipid secretion over a period of 8 h with intact enterohepatic circulation and 4 h with complete
S Pourbaix et al.
Biochemical pharmacology, 33(22), 3661-3666 (1984-11-15)
Hamsters were given a diet containing fenofibrate (0.5% or 0.05%) or its metabolite, LF 2151 (0.15% or 0.015%) or a standard diet for a 3-week period. At the end of this period, the analysis of plasma lipids showed that the
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