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E0753

Supelco

4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one

analytical standard, for drug analysis

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About This Item

Formule empirique (notation de Hill):
C12H11NO3
Numéro CAS:
15646-46-5
Poids moléculaire :
217.22
Numéro CE :
239-713-9
Numéro MDL:
MFCD00003204
Code UNSPSC :
41116107
ID de substance PubChem :
329798987
Nomenclature NACRES :
NA.24

Qualité

analytical standard, for drug analysis

Niveau de qualité

200

Pureté

≥90% (HPLC)

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Pf

94-96 °C (dec.) (lit.)

Application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

CCO\C=C1/N=C(OC1=O)c2ccccc2

InChI

1S/C12H11NO3/c1-2-15-8-10-12(14)16-11(13-10)9-6-4-3-5-7-9/h3-8H,2H2,1H3/b10-8-

Clé InChI

SJHPCNCNNSSLPL-NTMALXAHSA-N

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Catégories apparentées

Application

4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one has been used as a haptenizing agent, which can induce an inflammatory reaction in adult zebrafish intestinal tissues and this can be used as a model for gene expression studies of the two forms of inflammatory bowel disease like Crohn′s disease and ulcerative colitis.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Actions biochimiques/physiologiques

Oxazolone sensitizing agent

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H317

Conseils de prudence

P280

Classification des risques

Skin Sens. 1

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
0000325397
0000325400
0000325398
0000260547
0000260545

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Huile d’olive analytical standard

Supelco

47118

Huile d′olive

Amalie W Arildsen et al.
Frontiers in immunology, 12, 650621-650621 (2021-04-06)
Epidemiological studies have long reported that perturbations of the childhood microbiome increase the risk of developing allergies, but a causal relationship with atopic dermatitis remains unclear. Here we colonized germ-free mice at birth or at one or eight week-of-age to
Ann Laigaard et al.
Scientific reports, 10(1), 21204-21204 (2020-12-05)
Atopic dermatitis is a chronic eczema commonly observed among children in Western countries. The gut microbiota is a significant factor in the pathogenesis, and ways to promote intestinal colonizers with anti-inflammatory capabilities are therefore favorable. The present study addressed the
Comparison of two chemically-induced colitis-models in adult zebrafish, using optical projection tomography and novel transcriptional markers
Haarder S, et al.
The Open Immunology Journal, 6, 154-154 (2016)
E J Putz et al.
PloS one, 14(10), e0223483-e0223483 (2019-10-10)
Hapten contact hypersensitivity (CHS) elicits a well-documented inflammation response that can be used to illustrate training of immune cells through hapten-specific CHS memory. The education of hapten-specific memory T cells has been well-established, recent research in mice has expanded the
Thomas Nolte et al.
Disease models & mechanisms, 6(1), 125-134 (2012-07-24)
Animal models mimicking human diseases have been used extensively to study the pathogenesis of autoimmune diseases and the efficacy of potential therapeutics. They are, however, limited with regard to their similarity to the human disease and cannot be used if
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