Journal of neurochemistry, 126 Suppl 1, 125-141 (2013-07-24)
Friedreich's ataxia is a debilitating progressive neurodegenerative disease associated with cardiomyopathy and other features. The underlying cause is a deficiency of the mitochondrial protein frataxin which causes mitochondrial iron deposition, increased oxidative stress and impaired adenosine triphosphate production. Over the
[The use of idebenone (noben) in neurological practice].
I V Damulin
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 106(11), 66-71 (2006-12-21)
Expert opinion on drug delivery, 9(11), 1377-1392 (2012-10-23)
Idebenone (IDE) is an antioxidant compound, structurally related to coenzyme Q10. Its therapeutic potential is growing in different application areas, as demonstrated by the number of experimental works and patents produced in very recent years. Cyclodextrin inclusion complexes, liposomes, microemulsions
Archives of gerontology and geriatrics, 8(3), 299-305 (1989-05-01)
The effects of idebenone on the swelling of rat brain mitochondria were studied. When FeCl3 was added to a mitochondrial suspension, a pronounced mitochondrial swelling occurred accompanied by the production of lipid peroxide; the two phenomena were closely correlated (r
Idebenone - monograph.
Alternative medicine review : a journal of clinical therapeutic, 6(1), 83-86 (2001-02-24)
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..