MABF301

Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1

clone 7B1.1, from mouse

• Synonyme(s) : Interleukin-7, IL-7
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Niveau de qualité: 100
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: 7B1.1, monoclonal
• Espèces réactives: human
• Technique(s): flow cytometry: suitable; western blot: suitable
• Isotype: IgG2aκ
• Numéro d'accès NCBI: NP_000871
• Numéro d'accès UniProt: P13232
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... IL7(3574)

Description

Description générale

The protein named IL-7, or interleukin 7 is a hematopoietic growth factor secreted by stromal cell in the bone marrow and thymus but also produced by many other cell types including keratinocytes, epithelial cells, hepatocytes and macrophage/dendritic cells but not by classical lymphocytes. IL7 is a cytokine that has multiple functions and is critical for proper T cell maturation and lymphoid cell survival, and its expression stimulates the proliferation of B cells, T cell and NK cells. IL-7 is detected by cells via its receptor and binding results in a cascade of signals important for T cell development and for T cell survival within the periphery, as well as memory T cells. IL-7 expression is upregulated in various lymphomas and leukemias and because of its effects on T cell development IL-7 is being examined as a therapeutic agent for transplantation studies and even latent viral infection studies.

Immunogène

GST-tagged recombinant protein corresponding to human Interleukin-7/IL-7.

Application

Flow Cytometry Analysis: 1 µg of this antibody detected recombinant Interleukin-7/IL-7 in Jurkat T and Raji B lymphocytes.

This Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1 is validated for use in western blotting & flow cytometry for the detection of Interleukin-7/IL-7.

Qualité

Evaluated by Western Blotting in Interleukin 7 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected 0.5 µg of recombinant Interleukin-7/IL-7.

Description de la cible

~ 17 kDa observed

Forme physique

Format: Purified

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable