Members of the SOX family of transcription factors are widely conserved and play important roles in early development and are often used as markers to assess the differentiation of specific cell lineages. SOX-15 (also known as SOX-20) is a nuclear, 25 kDa transcriptional repressor that belongs to group G of the SOX gene family. Sox-15 is widely expressed in fetal and adult tissues, with highest level found in fetal spinal cord, adult brain and adult testis. Recently, SOX-15 has been identified as having transcriptional control in mouse embryonic stem cells pluripotency along with SOX-2. SOX-15 is also expressed in myoblasts and regulates skeletal muscle regeneration and differentiation.
Immunogène
GST-tagged recombinant protein corresponding to human SOX-15.
Application
Anti-SOX-15 Antibody, clone 1A2.1 is an antibody against SOX-15 for use in western blotting & ICC.
Immunocytochemsitry Analysis: A 1:50 dilution of this antibody detected SOX-15 in a undifferentiated H9 human embryonic stem cells.
Research Category Stem Cell Research
Research Sub Category Pluripotent & Early Differentiation
Qualité
Evaluated by Western Blotting in a undifferentiated H9 human embryonic stem cell lysate. Western Blotting Analysis: 1.0 µg/mL of this antibody detected SOX-15 in a undifferentiated H9 human embryonic stem cells.
Description de la cible
~ 36 kDa observed
Forme physique
Format: Purified
Protein G Purified
Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Stockage et stabilité
Stable for 1 year at 2-8°C from date of receipt.
Autres remarques
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
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