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HIFN-130K

Millipore

MILLIPLEX® Human Interferon Panel

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About This Item

Code UNSPSC :
12161503
Nomenclature NACRES :
NA.77
To order a Milliplex® kit, please search for your analyte of interest.
Design And Price Your Kit

Utilisation

 kit sufficient for 96 wells

Niveau de qualité

200

Espèces réactives

human

Paramètres

25 μL sample volume (per well)

Technique(s)

multiplexing: suitable

Méthode de détection

fluorometric (Luminex® xMAP®)

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Description générale

Interferons (IFNs) are widely expressed cytokines that have potent antiviral and antiproliferative effects. These cytokines are the first line of defense against viral infections and have important roles in immunosurveillance for malignant cells. IFNs are classified as type I, II and III IFNs, based upon the target receptors to which they bind. In humans, type I IFNs belong to a multigene family consisting of multiple IFNα subtypes but only one IFNβ, IFNε, IFNκ, and IFNω. There is only one type II IFN: IFNγ. The type III IFNs include IFNλ1, λ2 and λ3, which are also known as interleukin-29 (IL-29), IL 28A and IL-28B, respectively. Functionally, the type I and type III IFNs are induced during a viral infection and involved in host defense against viruses. IFNγ (type II) is primarily involved in the allergic response, in host defense against intracellular pathogens, and in control of tumor growth. Studies of IFNs have broadened the mechanistic understanding of cell signaling, gene transcription, and innate and acquired immunity.

Research category: Inflammation & ImmunologyResearch sub-category:

  • Inflammation & Autoimmune Mechanisms
  • Inflammation

Spécificité

There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.

Application

The MILLIPLEX® Human Interferon Magnetic Bead Panel is a 9-plex kit to be used for the simultaneous quantification of any or all of the following analytes in serum or plasma samples and tissue/cell lysate and culture supernatant samples: IFNα-2, IFNβ, IFNε, IFNɣ, IFNɣ Receptor 1, IFNλ1, IFNλ2, IFNλ3, IFNω.

Caractéristiques et avantages

Design your multiplex kit by choosing available analytes within this panel.

Informations légales

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

Organes cibles

Respiratory Tract

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Certificats d'analyse (COA)

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Contenu apparenté

How to Select Your Immunoassay Platform

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Immunology Multiplex Assays | MILLIPLEX® Assays

Immunology multiplex assays, like MILLIPLEX® assays, allow researchers to investigate more immune biomarkers simultaneously, saving time and resources. This is especially critical to immunology research, where numerous analytes play a role in different pathways.

Questions

  1. What is the correlation between IFNa2 and IFN-g between HCYTA-60K and HIFN-130K? Are the antibody pairs the same?

    1 answer

    1. The correlation values for IFN between the two panels are satisfactory:
      - IFN-g R2 = 0.9603, Slope = 0.8889
      - IFNa2 R2 = 0.9865, Slope = 1.0207
      Additionally, the antibody pairs are identical.

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