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AP503H

Sigma-Aldrich

Goat Anti-Chicken IgG (H+L) Antibody, PE conjugate

0.5 mg/mL, Chemicon®

Synonyme(s) :

IgY

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.46

Source biologique

goat

Niveau de qualité

Conjugué

PE

Forme d'anticorps

affinity purified immunoglobulin

Type de produit anticorps

secondary antibodies

Clone

polyclonal

Espèces réactives

chicken

Fabricant/nom de marque

Chemicon®

Concentration

0.5 mg/mL

Technique(s)

ELISA: suitable
immunofluorescence: suitable

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Description générale

IgG is one of the most abundant proteins in human serum. IgG is important for our defence against microorganisms and the molecules are produced by B-lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.

Spécificité

The antibody reacts with the heavy and light chains of chicken IgG as demonstrated by ELISA.

Immunogène

Epitope: Chicken IgG
Prepared from pooled antisera from goats hyperimmunized with chicken IgG.

Application

Goat anti-Chicken IgG (H+L) Antibody, PE conjugate is an antibody against Chicken IgG (H+L) for use in ELISA & IF.
Immunofluorescence: ≤0.2 μg/106 cells.
ELISA

Optimal working dilutions must be determined by the end user.
Research Category
Secondary & Control Antibodies
Research Sub Category
Whole Immunoglobulin Secondary Antibodies

Forme physique

Affinity Chromatography
Purified by affinity chromatography on chicken IgG covalently linked to agarose. Liquid in 1.0 mL of PBS/NaN3 and a stabilizing agent.

Stockage et stabilité

Maintain refrigerated at 2°-8°C under sterile conditions for up to twelve months from date of receipt. DO NOT FREEZE.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Luke F Pennington et al.
Nature communications, 12(1), 7069-7069 (2021-12-05)
Antibody drugs exert therapeutic effects via a range of mechanisms, including competitive inhibition, allosteric modulation, and immune effector mechanisms. Facilitated dissociation is an additional mechanism where antibody-mediated "disruption" of stable high-affinity macromolecular complexes can potentially enhance therapeutic efficacy. However, this
Michelle Cristiane Bufalo et al.
Cells, 11(2) (2022-01-22)
Increased collagen-derived advanced glycation end-products (AGEs) are consistently related to painful diseases, including osteoarthritis, diabetic neuropathy, and neurodegenerative disorders. We have recently developed a model combining a two-dimensional glycated extracellular matrix (ECM-GC) and primary dorsal root ganglion (DRG) that mimicked

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