5.05873

(R)-Baclofen

• Synonyme(s) : (R)-Baclofen, STX 209, GABA _B Agonist, Baclofen, Arbaclofen, STX 209, GABA_B Agonist, Baclofen, Arbaclofen
• Formule empirique (notation de Hill): C₁₀H₁₂ClNO₂
• Numéro CAS: 69308-37-8
• Poids moléculaire : 213.66
• Code UNSPSC : 12352200

Propriétés

• Pureté: ≥98% (HPLC)
• Niveau de qualité: 100
• Forme: solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; protect from light
• Couleur: off-white
• Solubilité: water: soluble
• Température de stockage: 2-8°C
• InChI: 1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)
• Clé InChI: KPYSYYIEGFHWSV-UHFFFAOYSA-N

Description

Description générale

A selective agonist of GABA_B receptors that is shown to activate K+ conductance in hippocampal neurons. Also acts as an antispastic agent and a skeletal muscle relaxant. It is also an experimental drug to treat autism.

Actions biochimiques/physiologiques

Primary Target
GABA_B

Avertissement

Toxicity: Toxic (F)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.

Autres remarques

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Sodickson, D.L., et al., 1996. J. Neurosci.16, 6374.

Ahuja, S. et al., 1985. Analytical Profile of Drug Substances14, 527.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H301
• Conseils de prudence: P264 - P270 - P301 + P310 - P405 - P501
• Classification des risques: Acute Tox. 3 Oral
• Code de la classe de stockage: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable