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F-903

Supelco

Fluphenazine dihydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Formule empirique (notation de Hill):
C22H26N3OSF3 · H2Cl2
Numéro CAS:
146-56-5
Poids moléculaire :
510.44
Numéro MDL:
MFCD00055212
Code UNSPSC :
41116107
ID de substance PubChem :
329799780
Nomenclature NACRES :
NA.24

Qualité

certified reference material

Forme

liquid

Caractéristiques

Snap-N-Spike®/Snap-N-Shoot®

Conditionnement

ampule of 1 mL

Fabricant/nom de marque

Cerilliant®

Concentration

1.0 mg/mL in methanol (as free base)

Technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Application(s)

clinical testing

Format

single component solution

Température de stockage

−20°C

InChI

1S/C22H26F3N3OS.2ClH/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29;;/h1-2,4-7,16,29H,3,8-15H2;2*1H

Clé InChI

MBHNWCYEGXQEIT-UHFFFAOYSA-N

Informations sur le gène

human ... DRD2(1813)

Description générale

Fluphenazine, sold under the trade name Prolixin®, is a typical antipsychotic prescribed for treatment of schizophrenia, mania, bipolar disorder and dementia. This certified solution standard is suitable for fluphenazine testing methods by GC/MS or LC/MS for clinical toxicology, forensic analysis, or urine drug testing applications.

Application


  • Monitoring Fluphenazine Metabolites in Schizophrenia: A study developed a radioimmunoassay for the 7-hydroxy metabolite of fluphenazine, applied to monitor plasma levels in patients treated long-term with oral and depot fluphenazine. This research enhances understanding of fluphenazine′s pharmacokinetics and aids in optimizing treatment regimens for schizophrenia, contributing to personalized medicine approaches (Aravagiri et al., 1994).

  • Neuroleptics in Clinical Practice: A review discusses the development and application of assays for neuroleptics, including fluphenazine, providing clinical perspectives on their use. This research is vital for enhancing therapeutic strategies and understanding the pharmacological profiles of antipsychotic drugs, which are crucial in treating severe mental disorders (Midha et al., 1993).

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Prolixin is a registered trademark of E.R. Squibb & Sons, LLC
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Pictogrammes

FlameSkull and crossbonesHealth hazard
GHS02,GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organes cibles

Eyes,Central nervous system

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

49.5 °F - closed cup

Point d'éclair (°C)

9.7 °C - closed cup

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Yu-Wen Chen et al.
European journal of pharmacology, 693(1-3), 31-36 (2012-08-29)
The aim of this study was to examine whether thioxanthine-type antipsychotics (chlorprothixene and cis(z)-flupenthixol) and phenothiazine-type antipsychotics (chlorpromazine and fluphenazine) produced spinal anesthesia. Using a rat model of intrathecal injection, we evaluated spinal anesthesia of antipsychotic drugs (chlorprothixene, cis(z)-flupenthixol, chlorpromazine
Martín Klappenbach et al.
Learning & memory (Cold Spring Harbor, N.Y.), 19(2), 73-83 (2012-01-24)
The understanding of how the reinforcement is represented in the central nervous system during memory formation is a current issue in neurobiology. Several studies in insects provide evidence of the instructive role of biogenic amines during the learning and memory
Antipsychotic medication for early-episode schizophrenia.
John R Bola et al.
Schizophrenia bulletin, 38(1), 23-25 (2011-11-26)
Irena Popović et al.
Psychiatria Danubina, 23(4), 384-388 (2011-11-15)
Schizophrenia is a severe chronic psychiatric disorder for which treatment compliance is important in the prevention of relapse. Second generation antipsychotics (SGA), such as Risperidone, have been found to be more effective in the treatment of such patients than the
David G Goodwin et al.
The Journal of parasitology, 97(1), 148-151 (2011-02-26)
An increasing interest in the association of the presence of antibodies to Toxoplasma gondii and the development of schizophrenia in patients has been generated over the last several years. Some antischizophrenia agents have been shown to have activity against T.
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