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D-067

Supelco

Digitoxin solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Formule empirique (notation de Hill):
C41H64O13
Numéro CAS:
71-63-6
Poids moléculaire :
764.94
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

certified reference material

Niveau de qualité

300

Forme

liquid

Caractéristiques

Snap-N-Spike®/Snap-N-Shoot®

Conditionnement

ampule of 1 mL

Fabricant/nom de marque

Cerilliant®

Concentration

1.0 mg/mL in methanol

Technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Application(s)

pharmaceutical (small molecule)

Format

single component solution

Température de stockage

−20°C

Chaîne SMILES 

CC1OC(CC(O)C1O)OC2C(O)CC(OC2C)OC3C(O)CC(OC3C)OC4CCC5(C)C(CCC6C5CCC7(C)C(CCC67O)C8=CC(=O)OC8)C4

InChI

1S/C41H64O13/c1-20-36(46)29(42)16-34(49-20)53-38-22(3)51-35(18-31(38)44)54-37-21(2)50-33(17-30(37)43)52-25-8-11-39(4)24(15-25)6-7-28-27(39)9-12-40(5)26(10-13-41(28,40)47)23-14-32(45)48-19-23/h14,20-22,24-31,33-38,42-44,46-47H,6-13,15-19H2,1-5H3

Clé InChI

WDJUZGPOPHTGOT-UHFFFAOYSA-N

Description générale

A cardiac glycoside and antiarrhythmic drug similar in structure and effect to digoxin. Digitoxin is monitored by clinical labs to ensure patients remain within the drug′s therapeutic range.

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Pictogrammes

FlameSkull and crossbonesHealth hazard
GHS02,GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organes cibles

Eyes,Central nervous system

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

49.5 °F - closed cup

Point d'éclair (°C)

9.7 °C - closed cup

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Certificats d'analyse (COA)

Lot/Batch Number

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Les clients ont également consulté

Slide 1 of 4

1 of 4

Digoxin analytical standard

Supelco

D6003

Digoxin

Digitonine, ultrapure CAS 11024-24-1 is a non-ionic detergent commonly used to solubilize membrane-bound proteins.

Millipore

300410

Digitonine, ultrapure

Digitonine ~50% (TLC)

Sigma-Aldrich

D5628

Digitonine

Digitonine Used as non-ionic detergent

Sigma-Aldrich

D141

Digitonine

Termination of refractory focal status epilepticus by the P-glycoprotein inhibitor verapamil.
S Pirker et al.
European journal of neurology, 18(12), e151-e151 (2011-11-22)
An elderly man with atrial fibrillation and exacerbated diabetes.
Ketil Arne Espnes et al.
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 132(9), 1103-1105 (2012-05-23)
Ryan Matsuda et al.
Journal of chromatography. A, 1265, 114-122 (2012-10-25)
High-performance affinity chromatography (HPAC) was used to examine the changes in binding that occur for the sulfonylurea drug glibenclamide with human serum albumin (HSA) at various stages of glycation for HSA. Frontal analysis on columns containing normal HSA or glycated
Arne Hønnås et al.
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 130(13), 1334-1336 (2010-07-03)
In 2007, new Norwegian guidelines suggested that serum concentrations of digitoxin should be in the interval 8 - 15 nmol/l, which is about 50 % lower than previous recommendations. We studied trends in dosing and serum concentrations of digitoxin in
Hosam A Elbaz et al.
Toxicology and applied pharmacology, 258(1), 51-60 (2011-11-01)
Mechanisms of digitoxin-inhibited cell growth and induced apoptosis in human non-small cell lung cancer (NCI-H460) cells remain unclear. Understanding how digitoxin or derivate analogs induce their cytotoxic effect below therapeutically relevant concentrations will help in designing and developing novel, safer
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