A-158

Amoxapine-D₈ solution

100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant^®

• Formule empirique (notation de Hill): C₁₇H₈D₈ClN₃O
• Numéro CAS: 1189671-27-9
• Poids moléculaire : 321.83
• Code UNSPSC : 41116107
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material
• Niveau de qualité: 300
• Forme: liquid
• Caractéristiques: Snap-N-Spike^®/Snap-N-Shoot^®
• Conditionnement: ampule of 1 mL
• Fabricant/nom de marque: Cerilliant^®
• Concentration: 100 μg/mL in methanol
• Technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Application(s): clinical testing
• Format: single component solution
• Température de stockage: −20°C
• InChI: 1S/C17H16ClN3O/c18-12-5-6-15-13(11-12)17(21-9-7-19-8-10-21)20-14-3-1-2-4-16(14)22-15/h1-6,11,19H,7-10H2/i7D2,8D2,9D2,10D2
• Clé InChI: QWGDMFLQWFTERH-UFBJYANTSA-N

Description

Description générale

This stable-labeled internal standard is suitable for quantification of amoxopine by LC-MS/MS or GC/MS for applications in clinical toxicology, forensic analysis, urine drug testing, pharmaceutical research, or therapeutic drug monitoring. Amoxopine is a tetracyclic antidepressant sold under notable trade names including Asendin^;, Asendis^;, Defanyl^; and Demolox^; for the treatment of major depressive disorder.

Application

• Amoxapine-D8 internal standard: Utilization of Amoxapine-D8 as an internal standard in mass spectrometry significantly enhances analytical accuracy, particularly in bioanalytical assays aimed at understanding the pharmacokinetics and metabolite profiling of Amoxapine. This application is essential for ensuring precise measurement in pharmaceutical research (Lin H et al., 2024).
• Stable isotope-labeled Amoxapine for biochemical studies: The use of stable isotope-labeled Amoxapine-D8 enables detailed studies on its metabolism and interaction with biological systems. This approach is crucial for developing a deeper understanding of its biochemical pathways and potential therapeutic effects (Al-Fakhrany OM et al., 2024).
• Amoxapine-D8 in pharmacological research: Research involving Amoxapine-D8 explores its pharmacological actions, especially its utility in treating conditions like depression and anxiety. By using deuterated versions, researchers can gain insights into the drug′s behavior in the body, improving the development of effective therapeutic regimens (Ainousah BE et al., 2024).
• High-purity Amoxapine-D8 for mass spectrometry: High-purity Amoxapine-D8 is critical for mass spectrometry applications where accuracy and minimal background noise are paramount. This purity level facilitates the study of complex biological samples, enabling more precise and reliable analytical outcomes (Sharma MK et al., 2024).

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02,GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H225,H301 + H311 + H331,H370
• Conseils de prudence: P210 - P280 - P302 + P352 + P312 - P304 + P340 + P311 - P370 + P378 - P403 + P235
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Code de la classe de stockage: 3 - Flammable liquids
• Point d'éclair (°F): 49.5 °F - closed cup
• Point d'éclair (°C): 9.7 °C - closed cup