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Principaux documents

841199C

Avanti

E. coli CA

Avanti Research - A Croda Brand 841199C

Synonyme(s) :

Cardiolipin (E. coli) (sodium salt)

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About This Item

Numéro CAS:
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Essai

>99% (TLC)

Forme

liquid

Conditionnement

pkg of 1 × 1 mL (841199C-10mg)

Fabricant/nom de marque

Avanti Research - A Croda Brand 841199C

Concentration

10 mg/mL (841199C-10mg)

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

O=P([O-])(OC[C@]([H])(OC(CCCCCCCC1C(C1)CCCCCCC)=O)COC(CCCCCCCCCCCCCC)=O)OCC([H])(O)COP([O-])(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCC/C=C/CCCCCCCC)=O)=O.[Na+].[Na+]

Description générale

Cardiolipin is a vital phospholipid of mitochondria.[1] E.coli membrane is made of 5-10% of cardiolipin.[2] Cardiolipin is a non-bilayer anionic phospholipid, that has four acyl chains and small headgroup.[3]

Actions biochimiques/physiologiques

Cardiolipin is implicated in the dynamic organization of membranes and in cell division.[2] It is critical in proton uptake pathway.[3]

Conditionnement

5 mL Clear Glass Sealed Ampule (841199C-10mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogrammes

Skull and crossbonesHealth hazard

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Organes cibles

Central nervous system, Liver,Kidney

Code de la classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

does not flash

Point d'éclair (°C)

does not flash


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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Mikhail Bogdanov et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(34), 15057-15062 (2010-08-11)
Phosphatidylcholine (PC) has been widely used in place of naturally occurring phosphatidylethanolamine (PE) in reconstitution of bacterial membrane proteins. However, PC does not support native structure or function for several reconstituted transport proteins. Lactose permease (LacY) of Escherichia coli, when
Javier Hoyo et al.
General physiology and biophysics, 39(2), 195-202 (2020-04-25)
The current strategies to eradicate bacteria require that the antimicrobial agent either penetrate or disrupt the bacterial membrane. In Escherichia coli (E.coli) as a model of Gram-negative strains, the antimicrobials have to cross two barriers - the outer and the
Targeting bacterial cardiolipin enriched microdomains: an antimicrobial strategy used by amphiphilic aminoglycoside antibiotics
El Khoury M, et al.
Scientific reports, 7(1), 10697-10697 (2017)
Cardiolipin synthases of Escherichia coli have phospholipid class specific phospholipase D activity dependent on endogenous and foreign phospholipids
Jeucken A, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1863(10), 1345-1353 (2018)
Functional role of cardiolipin in mitochondrial bioenergetics
Paradies G, et al.
Biochimica et Biophysica Acta - Bioenergetics, 1837(4), 408-417 (2014)

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