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810132P

Avanti

18:1-06:0 NBD PC

Avanti Research™ - A Croda Brand

Synonyme(s) :

1-oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine

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245.00 CHF
5 MG
362.00 CHF
10 MG
525.00 CHF

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1 MG
245.00 CHF
5 MG
362.00 CHF
10 MG
525.00 CHF

About This Item

Formule empirique (notation de Hill) :
C38H64N5O11P
Numéro CAS:
106974-05-4
Poids moléculaire :
797.92
Numéro MDL:
MFCD16661190
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

245.00 CHF

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Devis pour commande en gros

Essai

>99% (TLC)

Forme

powder

Conditionnement

pkg of 1 × 1 mg (810132P-1mg)
pkg of 5 × 1 mg (810132P-5mg)
pkg of 5 × 2 mg (810132P-10mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand

Conditions d'expédition

dry ice

Température de stockage

−20°C

Description générale

Phosphatidylcholine (PC) is a prime metabolite of glycerolipid metabolism in eukaryotes.[1] It is a vital component of the mucosal layer of the colon and a strong bilayer-forming lipid.[2] NBD PC has 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) moiety attached to phosphatidylcholine.[3]

Application

18:1-06:0 NBD PC is suitable:
  • for the generation of giant unilamellar vesicles (GUVs) subjected to fluorescence microscopy[4]
  • for labeling lipid bilayers formed by vesicle fusion in order to study the lipid distribution by fluorescence microscopy[5]
  • for the preparation of phospholipid-coated beads[6]

Actions biochimiques/physiologiques

7-nitrobenz-2-oxa-1,3-diazol-4-yl phosphatidylcholine (NBD PC) is used as a fluorescent probe in biological membranes to study the cellular processes.[3]

Conditionnement

5 mL Amber Glass Screw Cap Vial (810132P-10mg)
5 mL Amber Glass Screw Cap Vial (810132P-1mg)
5 mL Amber Glass Screw Cap Vial (810132P-5mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids

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Yuta Ryoden et al.
Journal of immunology (Baltimore, Md. : 1950), 204(3), 559-568 (2019-12-22)
In response to extracellular ATP, the purinergic receptor P2X7 mediates various biological processes, including phosphatidylserine (PtdSer) exposure, phospholipid scrambling, dye uptake, ion transport, and IL-1β production. A genome-wide CRISPR screen for molecules responsible for ATP-induced PtdSer exposure identified a transmembrane
Henry A Boumann et al.
Biochimica et biophysica acta, 1788(7), 1444-1451 (2009-04-21)
Anammox bacteria that are capable of anaerobically oxidizing ammonium (anammox) with nitrite to nitrogen gas produce unique membrane phospholipids that comprise hydrocarbon chains with three or five linearly condensed cyclobutane rings. To gain insight into the biophysical properties of these
Wan-Chen Lin et al.
Biophysical journal, 90(1), 228-237 (2005-10-11)
A fundamental attribute of cell membranes is transmembrane asymmetry, specifically the formation of ordered phase domains in one leaflet that are compositionally different from the opposing leaflet of the bilayer. Using model membrane systems, many previous studies have demonstrated the
Sang-Yeob Kim et al.
PloS one, 12(4), e0174603-e0174603 (2017-04-05)
The removal of unwanted or damaged cells by phagocytes is achieved via a finely regulated cleaning process called efferocytosis. To characterize the mechanisms through which phagocytes control the intake of apoptotic cells, we investigated how the phagocyte's appetite for engulfed
Johan Tornmalm et al.
Scientific reports, 9(1), 18133-18133 (2019-12-04)
Protein-lipid interactions in cellular membranes modulate central cellular functions, are often transient in character, but occur too intermittently to be readily observable. We introduce transient state imaging (TRAST), combining sensitive fluorescence detection of fluorophore markers with monitoring of their dark
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