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Merck
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920975

Sigma-Aldrich

TissueFab® bioink 

(GelAlgHA)ma -UV/365 nm

Synonyme(s) :

AlgMA, Alginate, Bioink, GelMA, Gelatin, HAMA, Hyaluronic acid

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About This Item

Code UNSPSC :
12352201
Nomenclature NACRES :
NA.25

Niveau de qualité

100

Description

suitable for 3D bioprinting applications

Stérilité

sterile-filtered

Forme

viscous liquid (or gel)

Impuretés

<5 CFU/g Bioburden (Fungal)
<5 CFU/g Bioburden (Total Aerobic)

Couleur

colorless to pale yellow

Taille des particules

0.2 μm

pH

(6.5-7.5)

Application(s)

3D bioprinting

Température de stockage

2-8°C

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Catégories apparentées

Application

TissueFab®- HAMA-AlgMA-UV bioink is an alginate methacrylate based bioink for 3D bioprinting applications. The formulation is optimized for 3D bioprinting of tissues and constructs using extrusion based 3D bioprinters, and can be can be used to bioprint cell-laden hydrogels in desired shape without any supporting material. The crosslinking of printed structures can be done in one step using UV light for further culture and maturation of cells for tissue engineering and regenerative medicine applications.

This bioink is derived from natural polymers − hyaluronic acid, alginate and gelatin. Hyaluronic acid is also known as sodium hyaluronate or hyaluronan, is an anionic, nonsulfated glycosaminoglycan (GAG). Alginate also known as sodium alginate or alginic acid, is a natural biopolymer obtained from brown algae. Alginate is a natural polysaccharide widely used in tissue engineering. Gelatin contains bioactive peptide sequences similar to native extracellular matrix which promotes integrin mediated cell adhesion and MMP sensitive enzymatic degradation which are essential for cellular functions such as migration, proliferation and differentiation.

Caractéristiques et avantages

  • Ready-to-use formulation optimized for high printing fidelity and cell viability, eliminating the lengthy bioink formulation development process
  • Step-by-step protocols developed and tested by MilliporeSigma 3D Bioprinting Scientists, no prior 3D bioprinting experience needed
  • Suitable for different extrusion-based 3D bioprinter model

Conditionnement

10 mL in glass bottle

Informations légales

TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Certificats d'analyse (COA)

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Articles

Bioink Selection for 3D Bioprinting

Bioinks enable 3D bioprinting of tissue constructs for drug screening and transplantation; select suitable bioinks for specific tissue engineering.

Recent Advances in 3D-Bioprinting-based Drug Screening

Learn how 3D bioprinting is revolutionizing drug discovery with highly-controllable cell co-culture, printable biomaterials, and its potential to simulate tissues and organs. This review paper also compares 3D bioprinting to other advanced biomimetic techniques such as organoids and organ chips.

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