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Merck
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Documents

915033

Sigma-Aldrich

TissueFab® bioink Bone

Vis/405 nm

Synonyme(s) :

3D Bioprinting, Bioink, GelMA, TissueFab

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About This Item

Code UNSPSC :
12352201
Nomenclature NACRES :
NA.23

Description

0.2 μm sterile filtered
suitable for 3D bioprinting applications

Niveau de qualité

100

Forme

gel form (viscous)

Impuretés

≤5 CFU/g Bioburden (Fungal)
≤5 CFU/g Bioburden (Total Aerobic)

Couleur

white

pH

6.5-7.5

Application(s)

3D bioprinting

Température de stockage

2-8°C

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Catégories apparentées

Application

TissueFab® - GelMA-Bone-Vis bioink is designed for promoting osteogenic differentiation of stem cells. It is based on Gelatin methacryloyl (GelMA) - Hydroxyapatite (HAp) hydrogel system. HAp is a highly crystalline form of calcium phosphate. HAp has a chemical similarity with the mineralized phase of bone which accounts for their excellent biocompatibility and osteoinductive and osteoconductive properties favorable for bone regeneration. HAp-containing hydrogels has been studied in literature to demonstrate their processability with different additive manufacturing approaches. Printing of cell laden structures with HAp containing bioink formulations have shown superior osteogenic properties.

Conditionnement

Product contains 10 ml of solution packaged in glass bottle.

Informations légales

TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 3

Certificats d'analyse (COA)

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Nano hydroxyapatite particles promote osteogenesis in a three-dimensional bio-printing construct consisting of alginate/gelatin/hASCs
Wang X F et al.
Royal Society of Chemistry Advances, 6, 6832-6842 (2016)
Tunable hydrogel composite with two-step processing in combination with innovative hardware upgrade for cell-based threedimensional bioprinting.
Wust S. et al.
Acta Biomaterialia, 10, 630-640 (2014)
Mehdi Sadat-Shojai et al.
Materials science & engineering. C, Materials for biological applications, 49, 835-843 (2015-02-18)
The ability to encapsulate cells in three-dimensional (3D) protein-based hydrogels is potentially of benefit for tissue engineering and regenerative medicine. However, as a result of their poor mechanical strength, protein-based hydrogels have traditionally been considered for soft tissue engineering only.
Michal Bartnikowski et al.
Materials (Basel, Switzerland), 9(4) (2016-04-14)
The concept of biphasic or multi-layered compound scaffolds has been explored within numerous studies in the context of cartilage and osteochondral regeneration. To date, no system has been identified that stands out in terms of superior chondrogenesis, osteogenesis or the
Xi Chen et al.
International journal of nanomedicine, 11, 4707-4718 (2016-10-04)
Periodontitis is a chronic infectious disease and is the major cause of tooth loss and other oral health issues around the world. Periodontal tissue regeneration has therefore always been the ultimate goal of dentists and researchers. Existing fabrication methods mainly
Afficher tous les articles scientifiques apparentés

Articles

Bioink Selection for 3D Bioprinting

Bioinks enable 3D bioprinting of tissue constructs for drug screening and transplantation; select suitable bioinks for specific tissue engineering.

Recent Advances in 3D-Bioprinting-based Drug Screening

Learn how 3D bioprinting is revolutionizing drug discovery with highly-controllable cell co-culture, printable biomaterials, and its potential to simulate tissues and organs. This review paper also compares 3D bioprinting to other advanced biomimetic techniques such as organoids and organ chips.

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

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